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Showing 305–320 of 667 results
Hp1404 is a novel cationic antimicrobial peptide. Hp1404 has specific inhibitory activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). The antibacterial activity, low toxicity, and low propensity to induce drug resistance of Hp1404 make it suitable for research on antibacterial agents. Product Details Product Name Hp1404 Biological activity Hp1404 is a novel cationic antimicrobial…
HPA3NT3-A2 is an analog of the HP (2-20) peptide and an antimicrobial peptide. HPA3NT3-A2 has antibacterial activity against multidrug-resistant strains. Product Details Product Name HPA3NT3-A2 Biological activity HPA3NT3-A2 is an analogue of the HP (2-20) peptide, antimicrobial peptide. HPA3NT3-A2 shows antimicrobial activities against multi-reagent resistant bacteria strains. Sequence Ala-Lys-Arg-Leu-Lys-Lys-Leu-Ala-Lys-Lys-Ile-Trp-Lys-Trp-Lys-NH2 Sequence Shortening AKRLKKLAKKIWKWK-NH2 Storage Please store…
HR1 is a papain-like protease. HR1 increases the permeability of human erythrocyte membranes. HR1 can induce permeabilization of the bacterial cytoplasmic membrane and can also induce permeabilization of mast cell plasma membranes. Product Details Product Name HR1 Biological activity HR1 is a mastoid protease. HR1 can increase the permeability of human erythrocyte membrane. HR1 can…
Hs-1 is an antimicrobial peptide that provides 80% protection against dengue-2 virus. Product Details Product Name Hs-1 Biological activity Hs-1 is an antimicrobial peptide displays 80% protection against the dengue-2 virus . Sequence Phe-Leu-Pro-Leu-Ile-Leu-Pro-Ser-Ile-Val-Thr-Ala-Leu-Ser-Ser-Phe-Leu-Lys-Gln-Gly Sequence Shortening FLPLILPSIVTALSSFLKQG Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Hs02, a cationic amphipathic antimicrobial peptide derived from a human protein, is the membrane-active module of the core chimeric peptide Chim2. Hs02 exhibits broad-spectrum and potent antibacterial activity against a variety of human pathogens, with MIC values as low as 2 ??M against Staphylococcus aureus and Escherichia coli and MBC values of 2-4 ??M. Hs02…
Human ??-defensin 5 is an antiviral peptide. Human ??-defensin 5 blocks infection by non-enveloped viruses, including AdV, HPV, and polyomavirus (IC50: 0.6-1.25 ??M against HPV16). Human ??-defensin 5 can bind to viral capsids and prevent virus escape from endosomes. Human ??-defensin 5 increases the binding of HIV to the cell surface. Human ??-defensin 5 also…
Human ??-Defensin 6 is a cysteine-rich peptide containing 32 residues that inhibits bacterial invasion and contributes to mucosal immunity. Human ??-Defensin 6 forms ordered self-assembled fibrils and nanonets that surround and entangle bacteria after random binding to bacterial surface proteins. Human ??-Defensin 6 also inhibits Candida albicans biofilm formation. Product Details Product Name Human ??-Defensin…
Human ??-defensin-1 (H??D-1) is an antimicrobial peptide and immunomodulator that induces fibroblasts to secrete angiogenin through EGFR, JNK, NF-??B, Src, and p38 signaling pathways, and binds CCR6 to activate G protein signaling, while also inducing ER stress, apoptosis, cell cycle arrest, and autophagy. Human ??-defensin-1 can be used in research on hepatocellular carcinoma, influenza A…
Human ??-defensin-2 (H??D-2) is an orally active, cysteine-rich antimicrobial peptide secreted by epithelial cells, with antibacterial, antiviral, and immunomodulatory activities. Human ??-defensin-2 binds CCR2, reduces NF-??B phosphorylation, increases CREB phosphorylation, inhibits pro-inflammatory cytokines, induces IL-10, and chemoattracts immune cells via CCR2/CCR6. Human ??-defensin-2 reduces smoke-induced pulmonary neutrophilia in mice, downregulates pulmonary pro-inflammatory signaling, promotes bacterial…
Human Defensin-5 (1-9) is an orally active antimicrobial peptide. Human Defensin-5 (1-9) inhibits metabolic disorders induced by a Western diet (WSD) or a fructose-containing Western diet (WSDF). Human Defensin-5 (1-9) enhances intestinal barrier function by upregulating the gene expression of ileal tight junction proteins and mucins. Human Defensin-5 (1-9) can be used in research on…
Human Histatin 1 is a histidine-rich peptide. Human Histatin 1 can be isolated from saliva. Human Histatin 1 promotes cell-matrix and cell-cell adhesion. Product Details Product Name Human Histatin 1 Biological activity Human Histatin 1 is a histidine-rich peptide. Human Histatin 1can be isolated from saliva. Human Histatin 1 promotes cell-substrate and cell-cell adhesion. Sequence…
HVF18-a3-d is an antimicrobial peptide. HVF18-a3-d reduces NO production. HVF18-a3-d inhibits the production of TNF-?? and IL-6, reduces ROS production, and inhibits the TLR4 signaling pathway and LPS-induced phosphorylation of ERK, JNK, and p38 MAPK. HVF18-a3-d exhibits antibacterial activity against a variety of bacteria by disrupting the bacterial outer and inner membranes. HVF18-a3-d protects mice…
HYNIC-UBI29-41 is composed of the bifunctional chelator HYNIC and the antimicrobial peptide UBI 29-41 (HY-P10364). HYNIC-UBI29-41 retains the antibacterial properties of UBI 29-41 and exhibits good affinity for both Gram-positive and Gram-negative bacteria. When labeled with the radionuclide Technetium (99mTc), HYNIC-UBI29-41 can serve as an imaging agent for detecting bacterial infections in mouse models. Product…
IDR 1002 is an anti-infective peptide that enhances the ability of human monocytes to migrate toward chemokines on fibronectin. IDR-1002 also induces adhesion and activation of ??1-integrin, with a mechanism that promotes monocyte recruitment. Product Details Product Name IDR 1002 Biological activity IDR-1002 is an anti-infective peptide that enhances the ability of human monocytes to…
IDR-1 is an antimicrobial peptide active against Gram-positive and Gram-negative bacteria. IDR-1 resists infection by selectively modulating innate immunity without significant toxicity. IDR-1 has anti-inflammatory and anti-infective properties, enhances the levels of monocyte chemokines, and attenuates the release of pro-inflammatory cytokines. Product Details Product Name IDR-1 Biological activity IDR-1 is an antimicrobial peptide that is…
IDR-1018 is an innate defense regulator conjugate with an MIC of 16 ??g/mL against MRSA USA300 LAC, MRSA SAP 0017, and S. epidermidis ATCC14990. IDR-1018 can be used to synthesize V-IDR1018 (vancomycin-innate defense regulator conjugate). Product Details Product Name IDR-1018 Biological activity IDR-1018 is an innate defense regulator conjugate, with MICs of 16 ??g/mL for…
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