Antimicrobial Peptides

TLN-58 is an antimicrobial peptide. TLN-58 has antibacterial activity against S. aureus, S. epidermidis, and group A Streptococcus. TLN-58 also induces upregulation of inflammatory cytokine mRNA in normal human keratinocytes and NCL-SG3 cells. Product Details Product Name TLN-58 Biological activity TLN-58 is an antimicrobial peptide. TLN-58 has antibacterial activity against S. aureus, S. epidermidis, and…

TLP-3, a Temporin L (HY-P2523) analog, is a SARS-CoV-2 main protease (Mpro) inhibitor with an IC50 of 7.0 ??M. TLP-3 inhibits protease activity by forming stable hydrogen bonds and hydrophobic interactions with key enzyme residues. TLP-3 can be used in research on SARS-CoV-2 infection. Product Details Product Name TLP-3 Biological activity TLP-3, Temporin L (HY-P2523)…

TP4 (Nile tilapia piscidin) is an orally effective amphipathic ??-helical cationic antimicrobial peptide. TP4 (Nile tilapia piscidin) exerts broad-spectrum bactericidal activity against both Gram-positive and Gram-negative bacteria by disrupting cell membrane structures, while also showing some hemolytic activity. TP4 (Nile tilapia piscidin) can modulate the innate immune system and enhance the expression of lysozyme, cytokines,…

Tritrpticin is a porcine antimicrobial peptide with membrane disruption and hemolytic properties. Tritrpticin disrupts the membranes of bacteria, fungi, and Jurkat T-cell leukemia cells and induces their death. Tritrpticin also enhances the efficacy of Metronidazole (HY-B0318) against Trichomonas vaginalis, reduces plasma endotoxin and inflammatory cytokine levels, limits bacterial growth in blood and visceral tissues, reduces…

Unguisin A is a cyclic peptide that can be isolated from the marine-derived fungus Emericella unguis. Product Details Product Name Unguisin A Biological activity Unguisin A s a cyclic peptides that can be isolated from the marine-derived fungus Emericella unguis. Sequence Cyclo(Ala-Trp-{Oaa}-Ala-Val-Leu-Val) Sequence Shortening Cyclo(AW-{Oaa}-AVFV) Storage Please store the product under the recommended conditions in…

Unguisin B is a cyclic peptide that can be isolated from the marine-derived fungus Emericella unguis. Product Details Product Name Unguisin B Biological activity Unguisin B s a cyclic peptides that can be isolated from the marine-derived fungus Emericella unguis. Sequence Cyclo(Ala-Trp-{Oaa}-Ala-Val-Leu-Val) Sequence Shortening Cyclo(AW-{Oaa}-AVLV) Storage Please store the product under the recommended conditions in…

Urumin has antiviral activity against human influenza A virus. Urumin inhibits the growth of PR8 influenza virus (IC50: 3.8 ??M). Urumin targets the conserved stem of H1 hemagglutinin and can effectively neutralize drug-resistant H1 influenza viruses. Urumin protects young mice from lethal influenza infection. Product Details Product Name Urumin Biological activity Urumin has antiviral activity…

Vaccarin C (Compound VIII) is a cyclic heptapeptide with good antifungal activity, with MIC values of 6 ??g/mL against the pathogenic fungi and dermatophytes M. audouinii and T. mentagrophytes. Vaccarin C has high cytotoxicity against Dalton lymphoma ascites (DLA) and Ehrlich ascites carcinoma (EAC) cell lines, with IC50 values of 3.35 and 5.72 ??M, respectively….