CUSTOM PEPTIDE SYNTHESIS
QYAOBIO provides custom peptide synthesis for customers in worldwide
QYABIO provides reliable custom peptide synthesis service for researchers and scientists in worldwide for 15 years. Our wide synthesized peptides production involve from simple to long and challenging sequences on customers’ specifications.
Our expert team can provides high-quality, reliable, flexible and cost-effective solutions for cutting-edge research in life science, drug discover, vitro diagnostics development. Fluorescent labels, multiple disulfides, stable isotopes, and many others peptide modifications are also our specialties in custom synthesis.
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Custom peptide synthesis service
QYAOBIO has the capability to synthesize peptides at different purity levels from crude to ≥95%. Various scales from mg to kg to satisfy any aliquoting requirements. In addition, express delivery is available for urgent projects. Higher purity levels require additional production time and cost. We recommend specific purity for different applications.
We are able to synthesize peptide of 150 amino acids and above, longer peptides are combined by recombinant peptide technology.
CORE COMPETITION
Our advantages
Customer Centricity
We strive to provide the all-round positive experience for our customers in worldwide.
Operational Excellence
QYAOBIO is the leading and successful manufacturer of peptides synthesis in China.
Innovation and Technology
We strive to provide the all-round positive experience for our customers in worldwide.
Expert Team
Our expert team provides reliable capability and hands-on oriented solution for any challenge projects.
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Custom Synthesis Technology
Peptides synthesis is the chemical joining process of two or more amino acids via peptide bonds. The typical amide bonds are formed by condensation reaction of the carboxyl group and the amino group from the growing peptide chain.
Chemical Peptide Synthesis
Chemical peptide synthesis normally occurs from the C- to N-terminus direction, it is a precise step-wise addition of one amino acid at once.
Solid Phase Peptide Synthesis
Solid phase peptide synthesis starts with the C-terminal end anchoring to a resin polymer, then leaves the N terminal amine unit to attach another N-protected amino acid unit freely. Then, the newly added amino acid will undergo de-protection of N-terminal amine. Thereby, allows the addition of another N-protected amino acid unit.
The assembling continues by repeating cycle of coupling, washing, and de-protection reactions. The final peptide will be cleaved from the anchoring resin and purified once synthesis complete.
Liquid Phase Peptide Synthesis
Liquid phase peptide synthesis is ideal for short peptides, such as dipeptides.
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Peptide Purification Method
Despite the high efficiency of most peptide synthesis methods, many synthesis processes still generate undesired impurities, because of the incomplete deprotection, unwanted reactions between free protecting groups, truncation and/or deletion of amino acids, isomers.
Among these methods, RP-HPLC is the most widely purification process. Different from the conventional HPLC separates products by the concentration of polar solvents on mobile phase. RP-HPLC can capture hydrophobic molecules from aqueous solutions, then release them in function of hydrophobicity. This is easier to separate required peptides from undesired impurities.
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Synthetic peptide applications
Qyaobio has substantial and long-standing expertise in peptide synthesis. We provide the highest quality custom peptides, no matter how complex or unusual of peptide sequences.
Synthetic peptides are ideal for a wide variety of applications and research areas. These synthetic peptides play the critical role in MS-based protein discovery, characterization, and quantitative analysis, especially for proteins as early disease biomarkers.
In addition, synthetic peptides are also applied in clinical diagnosis and disease treatment. Including:
Grug & Gene Delivery
In advanced gene and drug delivery, cell-penerating peptides and self-assembling peptides are two critical bio-active components. Comparing to viral vectors, peptides are easier to synthesize with more accessible and widespread.
Peptide Drugs
Many peptide drugs are synthesized from chemical modification of natural molecules. These drugs are invaluable for multiple treatment of metabolic diseases.
Tissue Engineering
Peptides with cell adhesion and self-assembling provide new opportunity in tissue engineering. These peptides are useful bioactive molecules to support cellular growth and tissue regeneration.
Peptide Vaccines
Vaccine are the most successful strategies of modern medicine. Peptide vaccines are a cost-effective, safe and highly specific alternative for conventional vaccines.
Cosmetic Application
Cosmetic peptides have protective and regenerative properties, many personal care products harness the beneficial properties. Small cosmetic peptides can cross the skin carrier due to the easy diffusion. Peptides with antimicrobial in cream can prevent and treat skin conditions.
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