Therapeutic Peptides

NN1177 is a long-acting GLP-1/glucagon receptor co-agonist. NN1177 can induce a dose-dependent body weight loss in diet-induced obese (DIO) mice. Product Information Product Name NN1177 Molecular Weight 4570.07 Formula C206H323N51O66 Appearance Solid Color White to off-white Sequence His-{Aib}-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Tyr-Leu-Glu-Ser-Lys-Arg-Ala-Arg-Glu-Phe-Val-Gln-Trp-Leu-Leu-{Lys(gGlu-gGlu-Ser-Glu-Ser-gGlu-gGlu-C18 diacid)}-Thr-NH2 Sequence Shortening H-{Aib}-QGTFTSDLSKYLESKRAREFVQWLL-{Lys(γGlu-γGlu-Ser-Glu-Ser-γGlu-γGlu-C18 diacid)}-T-NH2 Storage Sealed storage, away from moisture Powder -80??C 2 years -20??C 1…

NN1213, a long-acting human amylin peptide analog, is a selective Amylin receptor agonist with EC50 values of 0.177?and 0.262 nM for hAMY3R and rAMY3R, respectively. NN1213 significantly reduces food intake and fat mass. NN1213 can reduce body weightin diet-induced obese rats. NN1213 can be used for the research of obesity. Product Information Product Name NN1213…

NOTA-AE105 is a uPAR-targeting PET imaging ligand. NOTA-AE105 can be radiolabeled with 64Cu and 68Ga. NOTA-AE105 binds to the urokinase-type plasminogen activator receptor, thereby enabling PET imaging of uPAR expression in tumor tissues. NOTA-AE105 can be used for research on head and neck squamous cell carcinoma, breast cancer, prostate cancer, bladder cancer, and glioblastoma. Product…

NOTA-P2-RM26 is an antagonist of Bombesin (HY-P0195) analogs, and the gastrin-releasing peptide receptor (GRPR/BB2) is a molecular target for prostate cancer visualization. NOTA-P2-RM26 is labeled with 111In and 68Ga for prostate cancer imaging studies using PET and SPECT/CT. Product Information Product Name NOTA-P2-RM26 Molecular Weight 1543.76 Formula C73H110N18O19 CAS Number 1446005-10-2 Appearance Solid Color White…

Octreotide (SMS 201-995) is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide (SMS 201-995) can bind to the somatostatin receptor and mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production. Octreotide (SMS 201-995) has antitumor activity, mediates apoptosis and may also be used in disease studies in…

Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently. Product Information Product Name Octreotide acetate Molecular Weight 1079.29 Formula C51H70N10O12S2 CAS Number 79517-01-4 Appearance Solid Color White to off-white Sequence {d-Phe}-Cys-Phe-{d-Trp}-Lys-Thr-{Cys(X)}-{Thr(deoxy)} (disulfide bridge: Cys2-Cys7) (X=N-(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl) Sequence Shortening {d-Phe}-CF-{d-Trp}-KY-{Cys(X)}-{Thr(deoxy)} (disulfide bridge: Cys2-Cys7) (X=N-(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl) Storage Sealed storage, away from…

Omramotide is an immunological agent for active immunization (antineoplastic). Product Information Product Name Omramotide Molecular Weight 1149.42 Formula C62H88N10O11 CAS Number 2306406-71-1 Sequence Phe-Leu-Pro-Phe-Gly-Phe-Ile-Leu-Pro-Val Sequence Shortening FLPFGFILPV

Onzigolide (BIM-23A760), a chimeric dopamine-somatostatin compound, shows potent agonist activity at both DA type 2 (D2R) and SST type 2 (SSTR2) receptors. Product Information Product Name Onzigolide Molecular Weight 1694.20 Formula C86H116N16O12S4 CAS Number 778630-77-6