Therapeutic Peptides

Mecasermin (Human IGF-I; FK 780) is a recombinant human insulin-like growth factor I (IGF-I). Mecasermin has the potential for the study of the growth failure of growth hormone (GH) insensitivity caused by GH receptor defects or GH-inhibiting antibodies. Product Information Product Name Mecasermin Molecular Weight 7645.68 Formula C331H512N94O101S7 CAS Number 68562-41-4 Appearance Liquid Color Colorless…

Melanotan I (MT-I; -α-MSH) acetate is an α-MSH (HY-P0252) analog, synthetic melanotropic peptide, and melanocortin receptor (MCR) agonist. Melanotan I acetate induces skin tanning by mimicking the action of α-MSH on the melanocortin 1 receptor (MC1R) in melanocytes. As an appetite suppressant, Melanotan I acetate impairs the ability of insulin to inhibit endogenous glucose production,…

MM-401 is a MLL1 H3K4 methyltransferase inhibitor. MM-401 inhibits MLL1 activity (IC50 = 0.32 ??M) by blocking MLL1-WDR5 interaction. MM-401 can induce cell cycle arrest, apoptosis and differentiation. MM-401 can be used for the research of MLL leukemia. Product Information Product Name MM-401 Molecular Weight 586.73 Formula C29H46N8O5 CAS Number 1442106-10-6

Motixafortide (BKT140 4-fluorobenzoyl) is a novel CXCR4 antagonist with an IC50 vakue of ??1 nM. Product Information Product Name Motixafortide Molecular Weight 2159.52 Formula C97H144FN33O19S2 CAS Number 664334-36-5 Appearance Solid Color White to off-white Sequence {4-Fluorobenzoyl}-Arg-Arg-{2-Naph-Ala}-Cys-Tyr-{Cit}-Lys-{d-Lys}-Pro-Tyr-Arg-{Cit}-Cys-Arg-NH2 (Disulfide bridge: Cys4-Cys13) Sequence Shortening {4-Fluorobenzoyl}-RR-{2-Naph-Ala}-CY-{Cit}-K-{d-Lys}-PYR-{Cit}-CR-NH2 (Disulfide bridge: Cys4-Cys13) Storage Sealed storage, away from moisture Powder -80??C 2 years…

Myelopeptide-2 is a peptide originally isolated from the supernatant of porcine bone marrow cell cultures, can restore mitogenic reactivity of human T lymphocytes inhibited by HL-60 leukemia cells or measles virus conditions. Myelopeptide-2 also recover depressed interleukin-2 (IL-2) synthesis and interleukin-2 receptor (IL-2R) expression. Myelopeptide-2 involves in immunity homeostasis, is perspective to be applied in…

N-Acetyl semax amidate is a derivative of Semax (HY-P1146) (Met-Glu-His-Phe-Pro-Gly-Pro) obtained via N-terminal acetylation and C-terminal amidation, and it exhibits nootropic and neuroprotective activities. N-Acetyl semax amidate exerts neuroprotective effects by upregulating the expression of BDNF and NGF, inhibiting neuronal apoptosis, alleviating oxidative stress, and reducing glutamate excitotoxicity. N-Acetyl semax amidate can be used in…

Nelipepimut-S (E75) is a peptide vaccine targeting HER2. When used in combination with granulocyte-macrophage colony-stimulating factor, Nelipepimut-S stimulates immune activity and induces anti-HER2 immune responses. Nelipepimut-S can be used in research related to breast cancer, triple-negative breast cancer and ductal carcinoma in situ. Product Information Product Name Nelipepimut-S Molecular Weight 995.21 Formula C50H78N10O11 CAS Number…

Nemifitide diTFA (INN 00835 diTFA) is a 5-HT2A receptor ligand that crosses the blood-brain barrier. Nemifitide diTFA is used in research related to major depressive disorder. Product Information Product Name Nemifitide diTFA Molecular Weight 922.80 Formula C37H45F7N10O10 CAS Number 204992-09-6 Appearance Solid Color White to off-white Sequence {Fluoro-Phe}-{Hyp}-Arg-Gly-Trp-NH2 Sequence Shortening {Fluoro-Phe}-{Hyp}-RGW-NH2 Storage Sealed storage, away…