Lixisenatide (Leu-13C6,15N) TFA is the 13C- and 15N-labeled Lixisenatide (HY-P0119). Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist. Lixisenatide inhibits the inflammatory response through down regulation of pro-inflammatory cytokines, and suppresses of the Akt-MEK1/2 signaling pathway. Lixisenatide can inhibit oxidative stress, mitochondrial dysfunction and apoptosis. Lixisenatide can be used for the researches of inflammation, metabolic…
Lixisenatide acetate is a glucagon-like peptide-1 (GLP-1) receptor agonist. Lixisenatide acetate inhibits the inflammatory response through down regulation of pro-inflammatory cytokines, and suppresses of the Akt-MEK1/2 signaling pathway. Lixisenatide acetate can inhibit oxidative stress, mitochondrial dysfunction and apoptosis. Lixisenatide acetate can be used for the researches of inflammation, metabolic disease, neurological disease and cardiovascular disease,…
Lobradimil (RMP 7), a synthetic bradykinin analog, is a potent and selective bradykinin B2 receptor agonist (Ki: 0.54 nM). Lobradimil increases the permeability of the BBB. Lobradimil can be used in the research of brain tumors. Product Information Product Name Lobradimil Molecular Weight 1098.28 Formula C49H75N15O12S CAS Number 159768-75-9 Appearance Solid Color White to off-white…
Lonodelestat (POL6014) is a potent, orally active and selective peptide inhibitor of human neutrophil elastase (hNE). Lonodelestat (POL6014) has the potential for the research of cystic fibrosis (CF). Product Information Product Name Lonodelestat Molecular Weight 1478.73 Formula C71H111N15O19 CAS Number 906547-89-5 Appearance Solid Color White to off-white Sequence cyclo({Aca}-Glu-Thr-Ala-Ser-Ile-Pro-{d-Pro}-{(2S)-2-aminodecanoyl}-Gln-Lys-Tyr-Pro-Pro) Sequence Shortening cyclo({Aca}-ETASIP-{d-Pro}-{(2S)-2-aminodecanoyl}-QKYPP) Storage Sealed storage,…
Lonodelestat TFA (POL6014 TFA) is a potent, orally active and selective peptide inhibitor of human neutrophil elastase (hNE). Lonodelestat TFA has the potential for the research of cystic fibrosis (CF). Product Information Product Name Lonodelestat TFA Molecular Weight 1592.75 Formula C73H112F3N15O21 Appearance Solid Color White to off-white Sequence cyclo Storage Sealed storage, away from moisture…
Lorutengitide is a transcriptional regulatory peptide, and exhibits antiproliferative efficacy. Product Information Product Name Lorutengitide Molecular Weight 714.76 Formula C30H50N8O12 CAS Number 2559326-61-1 Sequence {Hyp}-Gly-Gln-Glu-{Aib}-Leu-Ala Sequence Shortening {Hyp}-GQE-{Aib}-LA
Lufefolastat Tetraxetan is a covalent conjugate of a PSMA-targeted peptide ligand and Tetraxetan (HY-W053583), a DOTA-class chelator. When labeled with 225Ac, Lufefolastat Tetraxetan is applicable to research on prostate-specific membrane antigen (PSMA)-positive metastatic prostate cancer. Product Information Product Name Lufefolastat Tetraxetan Molecular Weight 2174.48 Formula C102H164N16O35 CAS Number 2934667-10-2
LVGRQLEEFL (mouse) can be named as G * peptide, corresponding to amino acids 113 to 122 in apolipoprotein J ( apoJ)}. LVGRQLEEFL (mouse) exhibits anti-inflammatory and anti-atherogenic properties. LVGRQLEEFL (mouse) can be added to an apoJ mimetic, to form HM-10/10 peptide, which is a mimetic peptide and a novel chimeric high density lipoprotein. HM-10/10 peptide…
Lys-Bradykinin (Kallidin (380-389) (human, porcine, bovine)) tetraacetate, a kind of kallidin and bradykinin receptor ligand, can be generated by kininogen protein through enzymatic cleavage by the protease kallikrein. Lys-Bradykinin tetraacetate, also a vasodilator, can widen blood vessels and increase blood flow. ys-Bradykinin stimulates net Na+ influx, and also the DNA synthesis. Lys-Bradykinin tetraacetate involves in…
Lysipressin (Lysine vasopressin ; -Vasopressin ) is a neurohypophyseal nonapeptide with dual cardiovascular regulatory activities of peripheral pressor action and central hypotensive action, and it also regulates pain perception in the body. Lysipressin is an Oxytocin Receptor agonist, with a Ki value of 10.2 nM for porcine OT receptor. Lysipressin stimulates contraction of rabbit bladder…
Lysipressin acetate (Lysine vasopressin acetate; -Vasopressin acetate) is a neurohypophyseal nonapeptide with dual cardiovascular regulatory activities of peripheral pressor action and central hypotensive action, and it also regulates pain perception in the body. Lysipressin acetate is an Oxytocin Receptor agonist, with a Ki value of 10.2 nM for porcine OT receptor. Lysipressin acetate stimulates contraction…
MACTIDE-V is an orally active and selective peptide-drug conjugate targeting CD206. MACTIDE-V delivers Verteporfin (HY-B0146) to CD206+ tumor-associated macrophages (TAM) to inhibit the YAP/TAZ signaling pathway, prompting YAP exclusion from the nucleus, inducing TAM polarization toward an anti-tumoral phenotype with enhanced phagocytosis and antigen presentation, and boosting T cell infiltration and NK cell activity. MACTIDE-V…
Macupatide (LY3532226) is a glucose-dependent insulinotropic polypeptide receptor (GIPR) agonist. Macupatide improves insulin secretory response and insulin sensitivity. Macupatide can be used in research on type 2 diabetes. Product Information Product Name Macupatide Molecular Weight 4984.60 Formula C232H357N49O72 CAS Number 2923558-68-1 Appearance Solid Color White to off-white Sequence Tyr-{Aib}-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-{2-Me-Leu}-Leu-Asp-Lys-{Lys-AEEA-AEEA-gGlu-C20 diacid}-His-Gln-{Aib}-Asp-Phe-Val-Glu-{pyridin-4-yl-Ala}-Leu-Leu-Glu-Ala-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 Sequence Shortening Y-{Aib}-EGTFISDYSI-{2-Me-Leu}-LDK-{Lys-AEEA-AEEA-gGlu-C20 diacid}-HQ-{Aib}-DFVE-{pyridin-4-yl-Ala}-LLEAGPSSGAPPPS-NH2 Storage…
MAGE-A1-derived peptide acetate is a short peptide sequence derived from MAGE-A1 protein. As a tumor-specific antigen, MAGE-A1-derived peptide acetate can be recognized and activated by cytotoxic T lymphocytes (CTLs), thereby generating an immune response to tumor cells expressing MAGE-A1. This immune response can lead to the lysis and death of tumor cells. MAGE-A1-derived peptide acetate…
Marlumotide is an immunological agent for active immunization, as well as an antineoplastic agent. Product Information Product Name Marlumotide Molecular Weight 2075.32 Formula C93H135N21O29S2 CAS Number 952720-86-4 Sequence Ser-Gly-Gln-Ala-Tyr-Met-Phe-Pro-Asn-Ala-Pro-Tyr-Leu-Pro-Ser-Cys-Leu-Glu-Ser Sequence Shortening SGQAYMFPNAPYLPSCLES
Mazdutide (IBI-362; LY-3305677) is a long-acting synthetic oxyntomodulin analog. Mazdutide is also a co-agonist of glucagon-like peptide (GLP-1R) and glucagon receptor (GCGR). Mazdutide binds human and mouse GCGR (Ki: 17.7 nM and 15.9 nM, respectively) and GLP-1R (Ki: 28.6 nM and 25.1 nM, respectively) and stimulates insulin secretion from mouse islets (EC50: 5.2 nM). Mazdutide…
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