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Showing 337–352 of 490 results
Pep-10L peptide is a glycoprotein VI (GPVI) antagonist with Ki values of 180, 225, and 179 ??M for CPR, GPO-1, and Type 1 collagen, respectively. Pep-10L peptide has anti-thrombotic effects. Product Information Product Name pep-10L peptide Molecular Weight 1484.52 Formula C69H89N13O24 CAS Number 1159846-95-3 Sequence Tyr-Ser-Asp-Thr-Asp-Trp-Leu-Tyr-Phe-Ser-Thr-Ser Sequence Shortening YSDTDWLYFSTS
Peptide 401, a potent mast cell degranulating factor from bee venom, suppresses the increased vascular permeability due to intradermal injection of various smooth muscle spasmogens (histamine, and 5-HT). Product Information Product Name Peptide 401 Molecular Weight 2587.22 Formula C110H192N40O24S4 CAS Number 32908-73-9 Appearance Solid Color White to off-white Sequence Ile-Lys-Cys-Asn-Cys-Lys-Arg-His-Val-Ile-Lys-Pro-His-Ile-Cys-Arg-Lys-Ile-Cys-Gly-Lys-Asn-NH2 (Disulfide bridge: Cys3-Cys15, Cys5-Cys19) Sequence…
Peptide YY (PYY) (3-36), Human is an endogenous appetite-suppressing peptide that acts as a selective agonist of neuropeptide Y (NPY) Y2 receptor. Peptide YY (PYY) (3-36), Human inhibits intestinal fluid secretion, colonic propulsion, and reduces fecal output in mouse models. Peptide YY (PYY) (3-36), Human inhibits dmPGE2-, 5HT (HY-B1473A)-, and Castor oil (HY-107799)-induced diarrhea in…
Petrelintide (ZP8396) is a dual amylin and calcitonin receptor agonist (DACRA) Petrelintide elicits a selective reduction in high-fat diet intake in diet-induced obese (DIO) rats, which is accompanied by a loss of fat mass and preservation of lean mass during weight reduction. Petrelintide can be utilized in diabetes research. Product Information Product Name Petrelintide Molecular…
Perelintide (ZP8396) acetate is a dual amylin and calcitonin receptor agonist (DACRA). Perelintide acetate elicits a selective reduction in high-fat diet intake in diet-induced obese (DIO) rats, which is accompanied by a loss of fat mass and preservation of lean mass during weight reduction. Perelintide acetate can be utilized in diabetes research. Product Information Product…
Pexiganan (MSI 78) is an orally active antimicrobial peptide with broad-spectrum bactericidal. Pexiganan disrupts bacterial cell membranes, induces peptidoglycan damage and cell lysis. Pexiganan TFA can be used for the research of bacterial infection. Product Information Product Name Pexiganan Molecular Weight 2477.17 Formula C122H210N32O22 CAS Number 147664-63-9 Appearance Solid Color White to off-white Sequence Shortening…
Pezadeftide (HXP124) is a naturally derived plant defensin peptide molecule with antifungal activity. Pezadeftide binds to fungal cell wall chitin and β-glucan, enters fungal cells via endocytosis; induces mitochondrial membrane hyperpolarization, promotes ROS generation, further triggers vacuole fusion, alters plasma membrane permeability, and ultimately causes fungal cell death. Pezadeftide exhibits inhibitory effects against various skin…
PKHB1 (txCD47) is a CD47 agonist and Thrombospondin-1 peptide mimetic. PKHB1 activates CD47 and triggers Caspase-independent, calcium-dependent cell death via mitochondrial alterations, ROS production, endoplasmic reticulum morphological changes, and dissipation of mitochondrial membrane potential. PKHB1 induces the exposure of Calreticulin, HSP70, and HSP90, thereby driving immunogenic cell death. PKHB1 promotes intratumoral CD8+ T cell infiltration…
PL-3994 is a natriuretic peptide receptor-A (NPR-A) agonist that is resistant to neutral endopeptidase and acts as a bronchodilator. PL-3994 produces concentration-dependent relaxation of pre-contracted guinea-pig trachea with an IC50 value of 42.7 nM. Product Information Product Name PL-3994 Molecular Weight 1875.18 Formula C82H127N27O20S2 CAS Number 952295-80-6
Plecanatide, an analogue of Uroguanylin, is an orally active guanylate cyclase-C (GC-C) receptor agonist. Plecanatide activates GC-C receptors to stimulate cGMP synthesis with an EC50 of 190 nM in T84 cells assay. Plecanatide shows anti-inflammatory activity in models of murine colitis. Product Information Product Name Plecanatide Molecular Weight 1681.89 Formula C65H104N18O26S4 CAS Number 467426-54-6 Appearance…
Plecanatide acetate, an analogue of Uroguanylin, is an orally active guanylate cyclase-C (GC-C) receptor agonist. Plecanatide acetate activates GC-C receptors to stimulate cGMP synthesis with an EC50 of 190 nM in T84 cells assay. Plecanatide acetate can be used for the research of chronic idiopathic constipation, and it also shows anti-inflammatory activity in models of…
PNC-27, a chimeric p53-penetratin peptide binds to HDM-2 in a p53 peptide-like structure, induces selective membrane-pore formation and leads to cancer cell lysis. PNC-27 is an anticancer peptide. PNC-27 can be used in acute myeloid leukemia research. Product Information Product Name PNC-27 Molecular Weight 4031.73 Formula C188H293N53O44S CAS Number 1159861-00-3 Appearance Solid Color White to…
PNC-27 acetate, a chimeric p53-penetratin peptide binds to HDM-2 in a p53 peptide-like structure, induces selective membrane-pore formation and leads to cancer cell lysis. PNC-27 acetate is an anticancer peptide. PNC-27 acetate can be used in acute myeloid leukemia research. Product Information Product Name PNC-27 acetate Molecular Weight 4031.73 (free base) Formula C188H293N53O44S.xC2H2O2 Appearance Solid…
PNC-28 is a peptide from the mdm-2-binding domain (residues 17?C26) of the p53 protein which contains a membrane crossing-penetratin sequence. PNC-28 can be used for pancreatic cancer research. Product Information Product Name PNC-28 Molecular Weight 3509.13 Formula C164H255N47O37S CAS Number 392661-17-5 Appearance Solid Color White to off-white Sequence Shortening ETFSDLWKLLKKWKMRRNQFWVKVQRG Sequence Shortening ETFSDLWKLLKKWKMRRNQFWVKVQRG Storage Sealed…
PNC-28 acetate is a peptide from the mdm-2-binding domain (residues 17?C26) of the p53 protein which contains a membrane crossing-penetratin sequence. PNC-28 acetate can be used for pancreatic cancer research. Product Information Product Name PNC-28 acetate Molecular Weight 3509.13 (free acid) Formula C164H255N47O37S.xC2HF3O2 Appearance Solid Color White to off-white Sequence Glu-Thr-Phe-Ser-Asp-Leu-Trp-Lys-Leu-Leu-Lys-Lys-Trp-Lys-Met-Arg-Arg-Asn-Gln-Phe-Trp-Val-Lys-Val-Gln-Arg-Gly Sequence Shortening ETFSDLWKLLKKWKMRRNQFWVKVQRG Storage…
Porcine dynorphin A (1-13) is a potent, endogenous ?? opioid receptor agonist and is antinociceptive at physiological concentrations. Product Information Product Name Porcine dynorphin A(1-13) Molecular Weight 1603.95 Formula C75H126N24O15 CAS Number 72957-38-1 Appearance Solid Color White to off-white Sequence Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys Sequence Shortening YGGFLRRIRPKLK Storage Sealed storage, away from moisture Powder -80??C 2 years -20??C…
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