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Showing 193–208 of 667 results
Cys-LL37 is a biomaterial with antibacterial properties developed through a method of covalent immobilization onto titanium surfaces. Cys-LL37 uses a flexible hydrophilic polyethylene glycol spacer and selective N-terminal coupling of LL37 to form a surface peptide layer that kills bacteria upon contact. Cys-LL37 can be used in research on the development of novel antibacterial biomaterials….
Cys-Pexiganan TFA is an amphipathic antimicrobial peptide. Cys-Pexiganan TFA has antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa, with MICs of 16 ??g/mL and 64.0 ??g/mL, respectively. Cys-Pexiganan TFA can interact with anionic phospholipids of microbial cell membranes and DNA, disrupting cells and causing cell death. Product Details Product Name Cys-Pexiganan TFA Biological activity Cys-Pexiganan…
CysHHC10 is a synthetic antimicrobial peptide showing potent antibacterial properties against both Gram-positive and Gram-negative bacteria. CysHHC10 has MIC values of 10.1 mM, 20.2 mM, 2.5 mM, and 1.3 mM against E. coli, P. aeruginosa, S. aureus, and S. epidermidis, respectively. Product Details Product Name CysHHC10 Biological activity CysHHC10 is a synthetic antimicrobial peptide (AMP),…
CysHHC10 TFA is a synthetic antimicrobial peptide showing potent antibacterial properties against both Gram-positive and Gram-negative bacteria. CysHHC10 TFA has MIC values of 10.1 mM, 20.2 mM, 2.5 mM, and 1.3 mM against E. coli, P. aeruginosa, S. aureus, and S. epidermidis, respectively. Product Details Product Name CysHHC10 TFA Biological activity CysHHC10 TFA is a…
CZEN-002 is an ??-melanocyte-stimulating hormone derivative with anti-inflammatory and antibacterial activities, inhibiting the production of TNF-??. Product Details Product Name CZEN-002 Biological activity CZEN-002 is a derivative of alpha-melanocyte-stimulating hormone that has anti-inflammatory and antibacterial properties, inhibiting the production of TNF-??. Sequence Chain 1:Cys-Lys-Pro-Val Chain 2:Cys-Lys-Pro-Val (Disulfide bridge:Chain 1 Cys1-Chain 2 Cys1) Sequence Shortening Chain…
d-(KLAKLAK)2, Proapoptotic Peptide is a pro-apoptotic peptide whose core mechanism of action is the disruption of organelle membranes, particularly mitochondrial membranes, thereby inducing apoptosis. d-(KLAKLAK)2, Proapoptotic Peptide activates caspase 3/7 activity in cancer cells. Although d-(KLAKLAK)2, Proapoptotic Peptide has very low toxicity to eukaryotic cells extracellularly, it cannot effectively penetrate cell membranes to enter the…
D-Cateslytin is an antimicrobial peptide with potent inhibitory activity against Candida albicans (MIC = 2.9 ??M). D-Cateslytin rapidly enters C. albicans cells, is non-cytotoxic to human gingival fibroblasts, and remains stable in saliva. D-Cateslytin can be used in research on C. albicans-related diseases, such as oral candidiasis. Product Details Product Name D-Cateslytin Biological activity D-Cateslytin…
D-K6L9 has antimicrobial and anti-biofilm activity against Pseudomonas aeruginosa (P. aeruginosa) from cystic fibrosis patients. D-K6L9 is stable, resistant to degradation by cystic fibrosis sputum proteases, and does not induce bacterial resistance. Product Details Product Name D-K6L9 Biological activity D-K6L9 shows antimicrobial and antibiofilm activities against P. aeruginosa from cystic fibrosis patients. D-K6L9 is stable…
d-KLA Peptide (D-(KLAKLAK)2), an isomer of KLA peptide (HY-P5345), is a pro-apoptotic peptide. d-KLA Peptide specifically targets mitochondria and induces apoptosis by disrupting the mitochondrial membrane. d-KLA Peptide increases caspase 3/7 activity, exerts a pro-apoptotic effect, and enhances anti-tumor efficacy in a mouse melanoma model. Product Details Product Name d-KLA Peptide Biological activity d-KLA Peptide…
d-WRL is a cationic antimicrobial peptide with salt tolerance, protease resistance, and no induction of drug resistance. d-WRL acts as a membrane-lytic agent that effectively kills planktonic MRSA, mature MRSA biofilms, and Pseudomonas aeruginosa. d-WRL selectively interacts with negatively charged bacterial membranes, causing changes in membrane permeability, structural disintegration, and leakage of intracellular contents, thereby…
Daptomycin is a lipopeptide antibiotic with rapid in vitro bactericidal activity against Gram-positive bacteria. Product Details Product Name Daptomycin Biological activity Daptomycin is a lipopeptide antibiotic with rapid in vitro bactericidal activity against gram-positive organisms. Molecular Weight 1620.67 Formula C72H101N17O26 CAS Number 103060-53-3 Appearance Solid Color Off-white to light yellow Sequence Dec-Trp-{d-Asn}-Asp-Thr-Gly-{Orn}-Asp-{d-Ala}-Asp-Gly-{d-Ser(Me)}-Glu-{Kynurenine} (Lactone: Thr4-Kynurenine13) Sequence…
DD-S067 is an antibacterial peptide. DD-S067 has multiple antibacterial mechanisms, including disruption of the bacterial inner and outer membranes and induction of reactive oxygen species (ROS) production, leading to lipid peroxidation. DD-S067 also inhibits the electron transport chain. DD-S067 exhibits potent antibacterial activity, with a GM value of 4.1 ??M against 27 multidrug-resistant strains. DD-S067…
Decoralin is a short-chain cationic ??-helical antimicrobial peptide that can be isolated from the venom of the decorative potter wasp (Oreumenes decoratus). Decoralin exhibits rapid and selective antibacterial activity by disrupting bacterial cell membranes. Decoralin can be used in antimicrobial research. Product Details Product Name Decoralin Biological activity Decoralin is a short cationic alpha-helical antimicrobial…
Defensin HNP 4 (HNP 4) is a host defense peptide with antibacterial activity against Gram-negative bacteria. Defensin HNP 4 inhibits ACTH-stimulated corticosterone (HY-B1618) synthesis in rat adrenal cell suspensions. Product Details Product Name Defensin HNP 4 Biological activity Defensin HNP 4 (HNP 4) is a host-defense peptide that has antimicrobial activity against Gram-negative bacteria. Defensin…
Defensin HNP-1 human is a human neutrophil peptide (HNP). Defensin HNP-1 human has immunomodulatory functions and delays neutrophil apoptosis. Defensin HNP-1 human has broad-spectrum antibacterial activity by inhibiting DNA/RNA/protein synthesis and interfering with metabolic pathways. Defensin HNP-1 human has direct inactivating effects on HIV, HSV-1, HSV-2, CMV, influenza virus, and others. Defensin HNP-1 human has…
Defensin HNP-1 human TFA is a human neutrophil peptide (HNP). Defensin HNP-1 human TFA has immunomodulatory functions and delays neutrophil apoptosis. Defensin HNP-1 human TFA has broad-spectrum antibacterial activity by inhibiting DNA/RNA/protein synthesis and interfering with metabolic pathways. Defensin HNP-1 human TFA has direct inactivating effects on HIV, HSV-1, HSV-2, CMV, influenza virus, and others….
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