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d-KLA Peptide

Description

d-KLA Peptide (D-(KLAKLAK)2), an isomer of KLA peptide (HY-P5345), is a pro-apoptotic peptide. d-KLA Peptide specifically targets mitochondria and induces apoptosis by disrupting the mitochondrial membrane. d-KLA Peptide increases caspase 3/7 activity, exerts a pro-apoptotic effect, and enhances anti-tumor efficacy in a mouse melanoma model.

Product Details

Product Name d-KLA Peptide
Biological activity d-KLA Peptide (D-(KLAKLAK)2), KLA peptide (HY-P5345) isomer, is a pro-apoptosis peptide. d-KLA Peptide can specifically target mitochondria and induce apoptosis by destroying the mitochondrial membrane. d-KLA Peptide increases caspase 3/7 activity, exerts proapoptotic activity and enhances antitumor efficacy in mouse melanoma models.
Molecular Weight 1523.99
Formula C72H138N20O15
CAS Number 286380-05-0
Appearance Solid
Color White to off-white
Sequence d-{Lys-Leu-Ala-Lys-Leu-Ala-Lys-Lys-Leu-Ala-Lys-Leu-Ala-Lys}
Sequence Shortening d-{KLAKLAKKLAKLAK}
Storage Sealed storage, away from moisture