SGNLTKYWKKIWKPGIKKWIK is an antimicrobial peptide targeting thymidylate kinase (TMK), with a KD value of 4.721 ??M. SGNLTKYWKKIWKPGIKKWIK exerts antibacterial effects through multiple mechanisms, including membrane disruption, induction of ROS, and DNA binding. SGNLTKYWKKIWKPGIKKWIK is significantly effective against Gram-negative bacteria, has good biocompatibility, and is not prone to inducing resistance. SGNLTKYWKKIWKPGIKKWIK can be used in research…
Siamycin I (BMY-29304) is a 21-residue tricyclic peptide and a secondary metabolite of actinomycetes. Siamycin I is an HIV fusion inhibitor, with an ED50 of 0.05-5.7 ??M against acute HIV type 1 (HIV-1) and HIV-2 infection. Siamycin I inhibits gelatinase and gelatinase biosynthesis-activating pheromone (GBAP) signaling in a non-competitive manner through the FsrC-FsrA two-component regulatory…
RP 71955 is an antimicrobial peptide with anti-HIV-1 activity. Product Details Product Name Siamycin III Biological activity RP 71955 is an antimicrobial peptide against HIV-1. Sequence Cys-Leu-Gly-Ile-Gly-Ser-Cys-Asn-Asp-Phe-Ala-Gly-Cys-Gly-Tyr-Ala-Val-Val-Cys-Phe-Trp (Lactam bridge: Cys1-Asp9(??-COOH), disulfide bridge:Cys1-Cys13;Cys7-Cys19) Sequence Shortening CLGIGSCNDFAGCGYAVVCFW (Lactam bridge: Cys1-Asp9(??-COOH), disulfide bridge:Cys1-Cys13;Cys7-Cys19) Storage Please store the product under the recommended conditions in the Certificate of Analysis.
SMAP-18 is a biologically active peptide (SMAP-18 is an 18-amino-acid-residue peptide amide and a truncated form of SMAP-29. Sheep myeloid antimicrobial peptide-29 (SMAP-29) has extremely high antibacterial activity against Pseudomonas strains, other Gram-negative bacteria, and multidrug-resistant pathogens. Compared with the parent SMAP-29, SMAP-18 shows higher cell selectivity because it has reduced hemolytic activity while retaining…
SMAP-29 is an antimicrobial peptide with LPS-binding and anti-inflammatory properties. SMAP-29 has broad-spectrum antibacterial activity against bacteria, fungi, and multidrug-resistant isolates. SMAP-29 kills pathogens by permeabilizing bacterial cell membranes, inducing depolarization and cell lysis, while also inhibiting inflammatory cytokines and reducing lethality in models of septic shock and pneumonia. SMAP-29 can be used in research…
soVIRIP is a viral inhibitory peptide with an IC50 of 1.2 ??M against HIV-1. soVIRIP binds to the HIV-1 GP41 fusion peptide, inhibiting viral fusion and entry into host cells. soVIRIP has broad-spectrum anti-HIV-1 activity and is non-toxic in zebrafish models. soVIRIP can be used in research on viral infections. Product Details Product Name soVIRIP…
SP-B peptide is an antimicrobial peptide. SP-B peptide has antifungal activity against Cryptococcus neoformans, Candida albicans, and Aspergillus fumigatus strains. Product Details Product Name SP-B peptide Biological activity SP-B peptide is an antimicrobial peptide. SP-B peptide has antifungal activity against strains of Cryptococcus neoformans, Candida albicans and Aspergillus fumigatus Sequence Ala-Pro-Pro-Gly-Ala-Arg-Pro-Pro-Pro-Gly-Pro-Pro-Pro-Pro-Gly-Pro-Pro-Pro-Pro-Gly-Pro Sequence Shortening APPGARPPPGPPPPGPPPPGP Storage…
SpHistin is an antimicrobial peptide (AMP). SpHistin can bind LPS (HY-D1056) and permeabilize bacterial membranes. The combination of SpHistin with rifampicin (HY-B0272) and azithromycin (HY-17506) promotes intracellular uptake of the antibiotics, thereby enhancing the bactericidal activity of both drugs against Pseudomonas aeruginosa. Product Details Product Name SpHistin Biological activity SpHistin is an antimicrobial peptide (AMP)….
Sphistin Synthetic Peptide (12-38, FITC in N-Terminal-Fluorescently Labeled Peptide) is a truncated fragment of the Sphistin synthetic peptide with potent antimicrobial activity. Product Details Product Name Sphistin Synthetic Peptide(12-38,Fitc in N-Terminal-Fluorescently Labeled Peptide) Biological activity Sphistin Synthetic Peptide (12-38, Fitc in N-Terminal-Fluorescently Labeled Peptide) is a truncated fragments of Sphistin Synthetic Peptide that shows potent…
SPR741 (NAB741) is a cationic peptide derived from polymyxin B and acts as a potentiator molecule. SPR741 increases the permeability of the outer membrane of Gram-negative bacteria and is used in research on severe Gram-negative bacterial infections. SPR741 inhibits multidrug-resistant Gram-negative bacteria. When used in combination with antibiotics, SPR741 has the ability to expand the…
SPR741 acetate (NAB741 acetate) is a cationic peptide derived from polymyxin B and acts as a potentiator molecule. SPR741 acetate increases the permeability of the outer membrane of Gram-negative bacteria and is used to inhibit severe Gram-negative bacterial infections. SPR741 acetate inhibits multidrug-resistant Gram-negative bacteria. When used in combination with antibiotics, SPR741 acetate has the…
SPR741 TFA (NAB741 TFA) is a cationic peptide derived from polymyxin B and acts as a potentiator molecule. SPR741 TFA increases the permeability of the outer membrane of Gram-negative bacteria and is used to inhibit severe Gram-negative bacterial infections. SPR741 TFA inhibits multidrug-resistant Gram-negative bacteria. When used in combination with antibiotics, SPR741 TFA has the…
Sublancin is a peptide with antibacterial activity that inhibits DNA replication, transcription, and translation without affecting membrane integrity. Sublancin inhibits glucose uptake by competitively binding the phosphotransferase system (PTS). Sublancin inhibits strain B. subtilis 168 ??SP??, with an MIC of 0.312 ??M. Product Details Product Name Sublancin Biological activity Sublancin is an antimicrobial peptide, which…
Suicin 65 is a type B antibiotic produced from Streptococcus suis and is active against all Streptococcus suis strains. Product Details Product Name Suicin 65 Biological activity Suicin 65 is a class I type B lantibiotic produced by Streptococcus suis. Suicin 65 is active against all S. suis isolates. Sequence Shortening GKNGVFK-{Abu}-IAHEAHMNAWQFLF-{Dhb}-AAS Storage Please store…
SVS-1 peptide is an anticancer peptide. SVS-1 peptide selectively recognizes cancer cells through electrostatic interactions, disrupts cell membrane structure, and leads to cell death. Unlike antimicrobial peptides, the efficacy of SVS-1 peptide occurs before complete neutralization of membrane charge. Product Details Product Name SVS-1 peptide Biological activity SVS-1 peptide is an anticancer peptide. SVS-1 peptide…
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