Dolcanatide is an orally active GC-C (guanylate cyclase-C) agonist. Dolcanatide shows laxative, anti-nociceptive and anti-inflammatory activity. Dolcanatide can be used in inflammatory bowel disease research. Product Information Product Name Dolcanatide Molecular Weight 1681.89 Formula C65H104N18O26S4 CAS Number 1092457-65-2 Appearance Solid Color White to off-white Sequence {d-Asn}–Asp-Glu-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-{d-Leu} (Disulfide bridge: Cys4-Cys12; Cys7-Cys15) Sequence Shortening {d-Asn}-DECELCVNVACTGC-{d-Leu} (Disulfide bridge:…
DOTA-CXCR4-L is a CXCR4 targeting peptide. DOTA-CXCR4-L can be used in the study of cancers, including glioblastoma and triple-negative breast cancer. NODAGA-LM3 can be labeled with / for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Product Information Product Name DOTA-CXCR4-L Molecular Weight 1223.34 Formula C58H78N16O14 Sequence cyclo Sequence Shortening cyclo
Application: Nuclear medicine Category: Chelate Peptides (DOTA) Condition / Topic: Cancer Layout: Freeze-dried in plastic vial Organism: Artificial Protein Name: Other Purity: >95% (HPLC-MS) Quantification: No Sequence: RGD-DPhe-Lys(DOTA), head-to-tail cyclized
DOTA-JR11 is a somatostatin receptor 2 ??SSTR2??antagonist. DOTA-JR11 can be labeled by 68Ga, used for paired imaging in neuroendocrine tumors (NETs) research. DOTA-JR11 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Product Information Product Name DOTA-JR11 Molecular Weight 1689.27 Formula C74H98ClN19O21S2 CAS Number 1039726-31-2 Appearance Solid Color White to off-white Sequence DOTA- Storage…
DOTA-LM3 is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 and 68 Ga-DOTA-LM3. 68 Ga-DOTA-LM3 shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns. 177Lu-DOTA-LM3 can be used for…
DOTA-LM3 TFA is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 TFA is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 TFA and 68 Ga-DOTA-LM3 TFA. 68 Ga-DOTA-LM3 TFA shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns….
DOTA-NOC (DOTA-Nal3-octreotide) is a high-affinity ligand of somatostatin receptor subtypes 2, 3 and 5. DOTA-NOC can be used for labeling with various radiometals, and development of radiopeptide imaging. DOTA-NOC can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Product Information Product Name DOTA-NOC Molecular Weight 1455.70 Formula C69H94N14O17S2 CAS Number 619300-53-7 Appearance Solid Color…
DOTATATE acetate is a DOTA-conjugated peptide. DOTATATE acetate can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide research (PRRT). DOTATATE (acetate) can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Product Information Product Name DOTATATE acetate Formula C65H90N14O19S2.xC2H4O2 CAS Number 177943-89-4 Appearance Solid Color White to off-white Sequence…
DRGN-1 is an antimicrobial peptide. DRGN-1 exhibits potent antibacterial and anti-biofilm activity, inhibiting Gram-negative and Gram-positive bacteria with EC50 values ranging from 0.50 to 4.62 ??M. DRGN-1 exerts its antibacterial effects by disrupting bacterial membrane permeability and mildly depolarizing the membrane potential. DRGN-1 inhibits biofilm formation of single species and mixed species of Pseudomonas aeruginosa…
Drosocin is a biologically active peptide (Drosocin is a 19-mer cationic antimicrobial peptide from Drosophila melanogaster. In Drosophila, the native drosocin protein carries a disaccharide moiety attached to a threonine residue at the middle position. This synthetic drosocin peptide has the same amino acid sequence without the disaccharide, and its activity is several-fold lower than…
Dusquetide (SGX942) is a first-in-class innate defense regulator (IDR). Dusquetide modulates the innate immune response to both PAMPs and DAMPs by binding to p62. Dusquetide shows activity in both reducing inflammation and increasing clearance of bacterial infection. DAMPs: damage-associated molecular patterns; PAMPs: pathogen-associated molecular patterns Product Information Product Name Dusquetide Molecular Weight 553.70 Formula C25H47N9O5…
Dusquetide (SGX942) TFA is a first-in-class innate defense regulator (IDR). Dusquetide TFA modulates the innate immune response to both PAMPs and DAMPs by binding to p62. Dusquetide TFA shows activity in both reducing inflammation and increasing clearance of bacterial infection. DAMPs: damage-associated molecular patterns; PAMPs: pathogen-associated molecular patterns Product Information Product Name Dusquetide TFA Molecular…
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