Dolcanatide
Description
Dolcanatide is an orally active GC-C (guanylate cyclase-C) agonist. Dolcanatide shows laxative, anti-nociceptive and anti-inflammatory activity. Dolcanatide can be used in inflammatory bowel disease research.
Product Information
| Product Name | Dolcanatide |
| Molecular Weight | 1681.89 |
| Formula | C65H104N18O26S4 |
| CAS Number | 1092457-65-2 |
| Appearance | Solid |
| Color | White to off-white |
| Sequence | {d-Asn}–Asp-Glu-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-{d-Leu} (Disulfide bridge: Cys4-Cys12; Cys7-Cys15) |
| Sequence Shortening | {d-Asn}-DECELCVNVACTGC-{d-Leu} (Disulfide bridge: Cys4-Cys12; Cys7-Cys15) |
| Storage | Stored under nitrogen, away from moisture Powder -80??C 2 years -20??C 1 year *In solvent : -80??C, 6 months; -20??C, 1 month (stored under nitrogen, away from moisture) |
