Sublancin
Description
Sublancin is a peptide with antibacterial activity that inhibits DNA replication, transcription, and translation without affecting membrane integrity. Sublancin inhibits glucose uptake by competitively binding the phosphotransferase system (PTS). Sublancin inhibits strain B. subtilis 168 ??SP??, with an MIC of 0.312 ??M.
Product Details
| Product Name | Sublancin |
| Biological activity | Sublancin is an antimicrobial peptide, which inhibits DNA replication, transcription and translation, without affecting membrane integrity. Sublancin suppresses glucose uptake for the competition of phosphotransferase system (PTS). Sublancin inhibits B. subtilis strain 168 ??SP?? with MIC of 0.312 ??M. |
| Formula | C162H254N50O51S5 |
| CAS Number | 207410-26-2 |
| Sequence | Gly-Leu-Gly-Lys-Ala-Gln-Cys-Ala-Ala-Leu-Trp-Leu-Gln-Cys-Ala-Ser-Gly-Gly-Thr-Ile-Gly-{Cys(D-glucopyranosyl)}-Gly-Gly-Gly-Ala-Val-Ala-Cys-Gln-Asn-Tyr-Arg-Gln-Phe-Cys-Arg (disulfide bridge: Cys7-Cys36, Cys14-Cys29) |
| Sequence Shortening | GLGKAQCAALWLQCASGGTIG-{Cys(D-glucopyranosyl)}-GGGAVACQNYRQFCR (disulfide bridge: Cys7-Cys36, Cys14-Cys29) |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
