Therapeutic Peptides

Balixafortide TFA (POL6326 TFA) is a potent, selective, well-tolerated peptidic CXCR4 antagonist with an IC50 < 10 nM. Balixafortide TFA shows 1000-fold selective for CXCR4 than a large panel of receptors including CXCR7. Balixafortide TFA blocks β-arrestin recruitment and calcium flux with IC50s < 10 nM. Balixafortide TFA is also a potent hematopoietic stem and...

Bamadutide (SAR425899) is a potent dual glucagon-like peptide-1 receptor/glucagon receptor (GLP-1R/GCGR) agonist. Bamadutide improves post-meal blood glucose control by significantly enhancing β-cell function and slowing down the rate of glucose absorption in the body. Bamadutide can be used for the research of metabolic diseases such as type 2 diabetes. Product Information Product Name Bamadutide Molecular…

Beinaglutide is a human GLP-1 polypeptide that shares almost 100% homology with human GLP-1 (7?C36). Beinaglutide displays does-dependent effects in glycemic control, inhibiting food intake and gastric empty and promoting weight loss. Beinaglutide has the potential for the research of overweight/obesity and nonalcoholic steatohepatitis (NASH). Product Information Product Name Beinaglutide Molecular Weight 3298.61 Formula C149H225N39O46…

Bentiromide is a peptide that is broken down in the pancreas by chymotrypsin. The bentiromide test is an excellent means of confirming the diagnosis of pancreatic exocrine insufficiency by outpatient test of chymotrypsin function. Product Information Product Name Bentiromide Molecular Weight 404.42 Formula C23H20N2O5 CAS Number 37106-97-1 Appearance Solid Color White to off-white Storage Sealed…

Bilpatide (RAY1225) is a dual agonist of glucagon-like peptide-1 receptor (GLP-1R) and glucose-dependent insulinotropic polypeptide receptor (GIPR). Bilpatide is applicable to research related to obesity and diabetes. Product Information Product Name Bilpatide Molecular Weight 4926.52 Formula C229H351N49O71 CAS Number 2869056-74-4 Sequence Tyr-{Aib}-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{Aib}-Leu-Asp-Lys-{Lys(IMDA-AEEA-AEEA-γGlu-C20 diacid)}-Ala-Gln-Lys-Ala-Phe-Val-Glu-Trp-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 (amide bridge: Lys17(IMDA)-Lys20) Sequence Shortening Y-{Aib}-EGTFTSDYSI-{Aib}-LDK-{Lys(IMDA-AEEA-AEEA-γGlu-C20 diacid)}-AQKAFVEWLIAGGPSSGAPPPS-NH2 (amide bridge: Lys17(IMDA)-Lys20)

BIO-11006 acetate, an analog of the MANS peptide, is a MARCKS (myristoylated alanine-rich C kinase substrate) inhibitor. Product Information Product Name BIO-11006 acetate Molecular Weight 1110.22 Formula C48H79N13O17 Appearance Solid Color White to off-white Storage Sealed storage, away from moisture Powder -80??C 2 years -20??C 1 year *In solvent : -80??C, 6 months; -20??C, 1…

Biotin-Oxytocin (Biotin-α-Hypophamine; Biotin-Oxytocic hormone) is a biological active peptide. (This is Oxytocin (HY-17571) N-terminally labeled with Biotin.) Product Information Product Name Biotin-Oxytocin Molecular Weight 1233.48 Formula C53H80N14O14S3 Appearance Solid Color White to off-white Sequence {Biotin}-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Disulfide bridge: Cys1-Cys6) Sequence Shortening {Biotin}-CYIQNCPLG-NH2 (Disulfide bridge: Cys1-Cys6) Storage Sealed storage, away from moisture Powder -80??C 2 years -20??C…

Bivalirudin, a hirudin analog and anticoagulant, is a direct thrombin inhibitor. Bivalirudin inhibits thrombin-mediated fibrinogen cleavage, coagulation factor activation, and platelet activation by reversibly binding to thrombin. In addition, Bivalirudin also has certain effects of anti-virus, anti-inflammation, and vascular endothelial barrier function protection. Bivalirudin can be used for the research of thrombotic diseases and others….