HYNIC-PSMA is a ligand for molecular imaging of tumors. Hynic-psma consists of two components: HYNIC (6-hydrazinonicotinamide) and PSMA (Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules, such as 188Re-HYNIC-PSMA. PSMA is a membrane antigen that is specifically expressed on the surface of prostate cancer cells. HYNIC-PSMA can be…
HYNIC-UBI29-41 is composed of the bifunctional chelator HYNIC and the antimicrobial peptide UBI 29-41 (HY-P10364). HYNIC-UBI29-41 retains the antibacterial properties of UBI 29-41 and exhibits good affinity for both Gram-positive and Gram-negative bacteria. When labeled with the radionuclide Technetium (99mTc), HYNIC-UBI29-41 can serve as an imaging agent for detecting bacterial infections in mouse models. Product…
Product Name Dynorphin B (1-9) Biological activity Dynorphin B (1-9) is a neuropeptide and N-terminal cleavage product of dynorphin B. The formation of dynorphin B (1-9) is blocked by N-ethylmaleimide (NEM), a non-selective inhibitor of cysteine peptidases. CAS Number 126050-26-8 Sequence Sequence Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe Sequence Shortening Sequence Shortening YGGFLRRQF Storage Please store the product under the…
Icatibant (HOE-140) is a potent and specific peptide antagonist of bradykinin B2 receptor with IC50 and Ki of 1.07 nM and 0.798 nM respectively. Product Information Product Name Icatibant Molecular Weight 1304.52 Formula C59H89N19O13S CAS Number 130308-48-4 Appearance Solid Color White to off-white Sequence Shortening RRPXGXSXXR Sequence Shortening RRPXGXSXXR Storage Sealed storage, away from moisture…
Icatibant acetate (HOE-140 acetate) is a potent and specific peptide antagonist of bradykinin B2 receptor with an IC50 and Ki of 1.07 nM and 0.798 nM respectively. Product Information Product Name Icatibant acetate Molecular Weight 1364.57 Formula C61H93N19O15S CAS Number 138614-30-9 Appearance Solid Color White to off-white Sequence Asp-Arg-Arg-Pro-Hyp-Gly-Thia-Thr-Thr-Arg-Asp-Phe-Ile-Glu-Ile-Ile-Trp-Arg-Lys-NH2 Sequence Shortening DRRP-Hyp-G-Thia-TTREDFIIWRK-NH2 Storage Sealed storage,…
Icotrokinra (JNJ-77242113) is an orally available, selective antagonist of the IL-23 receptor. Icotrokinra inhibits IL-23-induced STAT3 phosphorylation in peripheral blood mononuclear cells (IC50=5.6 pM) and inhibits IL-23-induced interferon IFN-γ production in NK cells with an IC50 of 18.4 pM. Icotrokinra exhibits anti-inflammatory activity in a rat TNBS-induced colitis model. Icotrokinra can be used in the…
Icotrokinra (JNJ-77242113) acetate is an orally available, selective antagonist of the IL-23 receptor. Icotrokinra acetate inhibits IL-23-induced STAT3 phosphorylation in peripheral blood mononuclear cells (IC50=5.6 pM) and inhibits IL-23-induced interferon IFN-γ production in NK cells with an IC50 of 18.4 pM. Icotrokinra acetate exhibits anti-inflammatory activity in a rat TNBS-induced colitis model. Icotrokinra acetate can…
IDR 1002 is an anti-infective peptide that enhances the ability of human monocytes to migrate toward chemokines on fibronectin. IDR-1002 also induces adhesion and activation of ??1-integrin, with a mechanism that promotes monocyte recruitment. Product Details Product Name IDR 1002 Biological activity IDR-1002 is an anti-infective peptide that enhances the ability of human monocytes to…
IDR-1 is an antimicrobial peptide active against Gram-positive and Gram-negative bacteria. IDR-1 resists infection by selectively modulating innate immunity without significant toxicity. IDR-1 has anti-inflammatory and anti-infective properties, enhances the levels of monocyte chemokines, and attenuates the release of pro-inflammatory cytokines. Product Details Product Name IDR-1 Biological activity IDR-1 is an antimicrobial peptide that is…
IDR-1018 is an innate defense regulator conjugate with an MIC of 16 ??g/mL against MRSA USA300 LAC, MRSA SAP 0017, and S. epidermidis ATCC14990. IDR-1018 can be used to synthesize V-IDR1018 (vancomycin-innate defense regulator conjugate). Product Details Product Name IDR-1018 Biological activity IDR-1018 is an innate defense regulator conjugate, with MICs of 16 ??g/mL for…
IDR-1018 acetate is an innate defense regulator conjugate with an MIC of 16 ??g/mL against MRSA USA300 LAC, MRSA SAP 0017, and S. epidermidis ATCC14990. IDR-1018 can be used to synthesize V-IDR1018 (vancomycin-innate defense regulator conjugate). Product Details Product Name IDR-1018 acetate Biological activity IDR-1018 acetate is an innate defense regulator conjugate, with MICs of…
IDR-HH2 is an immunomodulatory peptide with the ability to regulate the host cytokine/chemokine environment. IDR-HH2 promotes the adhesion of monocytes and THP-1 cells to fibronectin. IDR-HH2 also has bacteriostatic activity, inhibiting P. aeruginosa and S. aureus with MIC values of 75 ??g/mL and 38 ??g/mL, respectively. Product Details Product Name IDR-HH2 Biological activity IDR-HH2 is…
Product Name Neuropeptide FF Biological activity Neuropeptide FF (NPFF), an octapeptide belonging to the RF-amide family of peptides, is a NPFF1 and NPFF2 receptors agonist with Ki values of 2.82 nM and 0.21 nM, respectively. Neuropeptide FF induces abstinence syndrome, exerts antiopioid and analgesic effects, releases via calcium-dependent mechanisms from rat spinal cord, regulates memory,…
Product Name IGF-I (30-41) TFA Biological activity IGF-I (30-41) (TFA) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions). Sequence Sequence Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr Sequence Shortening Sequence Shortening GYGSSSRRAPQT Storage…
Product Name Allatostatin II Biological activity Allatostatin II is a decapeptid. Allatostatins are pleiotropic neuropeptides for inhibition of juvenile hormone synthesis in insects. CAS Number 123374-34-5 Sequence Sequence Gly-Asp-Gly-Arg-Leu-Tyr-Ala-Phe-Gly-Leu-NH2 Sequence Shortening Sequence Shortening GDGRLYAFGL-NH2 Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Product Name Calcitonin Gene Related Peptide II (rat) Biological activity Calcitonin Gene Related Peptide II rat, a CGRP receptor activator, is a potent and long-lasting vasodilator. Calcitonin Gene Related Peptide II rat can be used in the research of cardiovascular diseases. Molecular Weight 3805.31 Formula Formula C163H267N51O50S2 CAS Number 99889-63-1 Sequence Sequence Ser-Cys-Asn-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2 (Disulfide bridge:…
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