Protactin
Description
Protactin is a pentapeptide lactone that can be produced by the Streptomyces cucumerisporus strain L703-4 (ATCC 53784) and has significant antioxidant properties. Protactin can be converted to actinomycin Zp by ferricyanide oxidation. Actinomycin Zp exhibits potent antibacterial activity in vitro and has significant anti-tumor effects against P-388 leukemia in mouse models.
Product Details
| Product Name | Protactin |
| Biological activity | Protactin is a pentapeptide lactone produced by Streptomyces cucumeris strain L703-4 (ATCC 53784) with significant antioxidant properties. Protactin can be converted to actinomycin Zp by ferrocyanide oxidation. Actinomycin Zp exhibits potent antibacterial activity in vitro and has significant antitumor effects against P-388 leukemia in a mouse model. |
| Sequence | {2-NH2,3-OH,4-Me-Ph}-Thr-{d-Val}-Pro-{Sar}-Val (Lactone bridge: Thr1-Val5) |
| Sequence Shortening | {2-NH2,3-OH,4-Me-Ph}-T-{d-Val}-P-{Sar}-V (Lactone bridge: Thr1-Val5) |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
