Tachyplesin II
Description
Tachyplesin II is a broad-spectrum cationic antimicrobial peptide. Tachyplesin II has significant inhibitory effects against Gram-positive bacteria, Gram-negative bacteria, and some fungi. Tachyplesin II binds bacterial membrane lipopolysaccharide through positive charges, disrupts membrane integrity, and causes leakage of cellular contents. Tachyplesin II binds to the DNA minor groove, inhibits microbial replication, and also inhibits HIV-1 replication and hepatoma cell proliferation.
Product Details
| Product Name | Tachyplesin II |
| Biological activity | Tachyplesin II is a broad-spectrum cationic antimicrobial peptide. Tachyplesin II has significant inhibitory effects on Gram-positive bacteria, Gram-negative bacteria, and some fungi. Tachyplesin II binds to bacterial membrane lipopolysaccharides through its positive charge, disrupting membrane integrity and causing leakage of cellular contents. Tachyplesin II can bind to DNA grooves, inhibiting microbial replication, and also suppressing HIV-1 replication and the proliferation of liver cancer cells. |
| Sequence Shortening | RWCFRVCYRGICYRKCR (Disulfide bridge:Cys3-Cys16,Cys7-Cys12) |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
