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Thiostrepton

Description

Thiostrepton is an antibiotic that selectively inhibits FOXM1. FOXM1 binds to the YAP/TEAD complex. The binding of the YAP/TEAD/FOXM1 complex to gene regulatory regions that control the cell cycle may affect cell proliferation.

Product Details

Product Name Thiostrepton
Biological activity Thiostrepton is a thiazole antibiotic which selectively inhibits FOXM1. FOXM1 binds to YAP/TEAD complex. YAP/TEAD/FOXM1 complex binding at regulatory regions of genes governing cell cycle may impact cell proliferation.
Molecular Weight 1664.89
Formula C72H85N19O18S5
CAS Number 1393-48-2
Appearance Solid
Color White to off-white