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RT2

Description

RT2 is a tryptophan-rich cationic amphipathic antimicrobial peptide whose main targets include lipopolysaccharide (LPS) on the bacterial surface and intracellular DNA. RT2 binds LPS on the bacterial surface, interacts with cytoplasmic membrane phospholipids, promotes its rapid penetration through the bacterial cell membrane into the cell, and then binds to DNA and other cytoplasmic components, thereby exerting antibacterial effects. RT2 is expected to be used in research on acute and chronic infections caused by planktonic bacteria.

Product Details

Product Name RT2
Biological activity RT2 is a tryptophan-rich cationic amphipathic antibacterial peptide, with main targets including lipopolysaccharide (LPS) on the bacterial surface and intracellular DNA. RT2 binds to bacterial surface LPS, and interacts with cytoplasmic membrane phospholipids, enabling it to rapidly penetrate the bacterial cell membrane and enter the cell, and then bind to components such as DNA in the cytoplasmic membrane, thereby exerting antibacterial effects. RT2 is promising for research of acute and chronic infections caused by planktonic bacteria.
Sequence Asn-Gly-Val-Gln-Pro-Lys-Tyr-Arg-Trp-Trp-Arg-Trp-Trp-Arg-Arg-Trp-Trp-NH2
Sequence Shortening NGVQPKYRWWRWWRRWW-NH2
Storage Please store the product under the recommended conditions in the Certificate of Analysis.