Murepavadin TFA
Description
Murepavadin (POL7080) (TFA), a 14-amino-acid cyclic peptide, is a highly effective and specific antibiotic. Murepavadin exhibits potent antibacterial activity against P. aeruginosa, with MIC50 and MIC90 values of 0.12 mg/L. Murepavadin can also target the lipopolysaccharide transport protein D. Murepavadin can be used in research on bacterial drug resistance.
Product Details
| Product Name | Murepavadin TFA |
| Biological activity | Murepavadin (POL7080) (TFA), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic. Murepavadin exhibits a potent antimicrobial activity for P. aeruginosa with MIC50 and MIC90 values both of 0.12 mg/L. Murepavadin also can target the lipopolysaccharide transport portin D. Murepavadin can be used for the research of bacterial resistance. |
| Molecular Weight | 1667.83 |
| Formula | C73H112N22O16.C2HF3O2 |
| CAS Number | 3053070-05-3 |
| Appearance | Solid |
| Color | White to off-white |
| Sequence | Cyclo(Ala-Ser-{d-Pro}-Pro-Thr-Trp-Ile-{Dab}-{Orn}-{d-Dab}-{Dab}-Trp-{Dab}-{Dab}) |
| Sequence Shortening | Cyclo(AS-{d-Pro}-PTWI-{Dab}-{Orn}-{d-Dab}-{Dab}-W-{Dab}-{Dab}) |
