Alamethicin
Description
Alamethicin is a linear 20-amino-acid antibiotic that induces voltage-gated conductance in model and cell membranes. Alamethicin shows antibacterial activity against Gram-positive bacteria but not against Gram-negative bacteria. Alamethicin can form amphipathic ??-helical structures in biofilms.
Product Details
| Product Name | Alamethicin |
| Biological activity | Alamethicin is a linear 20-amino acid antibiotic, which can induce voltage-gated conductance in model and cell membranes. Alamethicin exhibits antimicrobial activity against Gram-positive bacteria, but not Gram-negative bacteria. Alamethicin can form an amphipathic ??-helical structure in biological membranes. |
| CAS Number | 27061-78-5 |
| Appearance | Solid |
| Color | White to yellow |
| Sequence | Ac-Aib-Pro-Aib-Ala-Aib-Ala-Gln-Aib-Val-Aib-Gly-Leu-Aib-Pro-Val-Aib-Aib-Glu-Gln-Phenylalaninol |
| Storage | Sealed storage, away from moisture |
