R2R01
Description
R2R01 is a potent and selective agonist of the relaxin family peptide receptor 1 (RXFP1), with an EC50 value of 0.34 nM. R2R01 activates RXFP1 to induce relaxin-like biological responses. R2R01 increases heart rate in both denervated and conscious rats. R2R01 can be used in research on cardiovascular diseases.
Product Details
| Product Name | R2R01 |
| Biological activity | R2R01 is a potent and selective relaxin family peptide receptor 1 (RXFP1) agonist with an EC50 of 0.34 nM. R2R01 activates RXFP1 to induce relaxin-like biological responses. R2R01 can increase heart rate in pithed and conscious rats. R2R01 can be used for the research of cardiovascular diseases. |
| Molecular Weight | 4361.12 |
| Formula | C197H344N48O61 |
| Sequence | AC-Leu-Glu-Gly-Arg-Glu-Lys-Val-Arg-Ala-Lys(AC)-Ile-{Aib}-{Aib}-Glu-Gly-Lys{(TTDS)3-??Glu-??Glu-??Glu-C16 acid}-Ser-Thr-Phe-Ser-{Mly}-Arg-Ala-Lys(Ac)-NH2 |
| Sequence Shortening | Ac-LEGREKVRA-Lys(AC)-I-{Aib}-{Aib}-EG-Lys{(TTDS)3-??Glu-??Glu-??Glu-C16 acid}-STFS-{Mly}-RA-Lys(Ac)-NH2 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
