Polymyxin B1
Description
Polymyxin B1 is a potent antibacterial lipopeptide derived from Paenibacillus polymyxa. Polymyxin B1 is the major component of Polymyxin B (HY-A0248). Polymyxin B1 induces bacterial cell lysis through interaction with the bacterial cell membrane. Polymyxin B1 can be used in research on multidrug-resistant Gram-negative bacterial infections.
Product Details
| Product Name | Polymyxin B1 |
| Biological activity | Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment. |
| Molecular Weight | 1203.48 |
| Formula | C56H98N16O13 |
| CAS Number | 816631 |
| Appearance | Solid |
| Color | White to off-white |
| Sequence | {Dab(6-methyl-1-oxooctyl)}-Thr-{Dab}-{Dab}-{Dab}-{d-Phe}-Leu-{Dab}-{Dab}-Thr (Lactam bridge: Dab4-Thr10) |
| Sequence Shortening | {Dab(6-methyl-1-oxooctyl)}-T-{Dab}-{Dab}-{Dab}-{d-Phe}-L-{Dab}-{Dab}-T (Lactam bridge: Dab4-Thr10) |
