Pac-525
Description
Pac-525 is a tryptophan-rich cationic antimicrobial peptide and membrane disruptor. Pac-525 has antibacterial activity against Gram-positive bacteria, Gram-negative bacteria, anaerobes, Candida albicans, and Fusarium solani. Pac-525 strongly interacts with negatively charged phospholipid vesicles, inducing dye release from vesicles and disrupting microbial membranes. Pac-525 is cytotoxic to macrophages. Pac-525 can be used in research on bacterial and fungal infections.
Product Details
| Product Name | Pac-525 |
| Biological activity | Pac-525 is a tryptophan-rich cationic antibacterial peptide and membrane-disrupting agent. Pac-525 exhibits antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, anaerobic bacteria, *Candida albicans* and *Fusarium solani*. Pac-525 interacts strongly with negatively charged phospholipid vesicles, induces vesicle dye release and disrupts microbial membranes. Pac-525 shows cytotoxicity against macrophages. Pac-525 can be used in studies related to bacterial and fungal infections. |
| CAS Number | 678967-50-5 |
| Sequence | Lys-Trp-Arg-Arg-Trp-Val-Arg-Trp-Ile |
| Sequence Shortening | KWRRWVRWI |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
