LANA
Description
LANA is the latency-associated nuclear antigen of Kaposi’s sarcoma-associated herpesvirus (KSHV). The core function of LANA is to serve as an “anchor” for the viral genome, tethering it to host cell chromatin. LANA ensures that KSHV episomal DNA replicates with host chromosomes and is evenly distributed to daughter cells, thereby maintaining latent viral infection in the cell population. LANA regulates viral and host cell gene transcription and regulates certain host cell genes to promote cell survival. LANA can be used in research on viral DNA tethering structures.
Product Details
| Product Name | LANA |
| Biological activity | LANA is a KSHV latency-associated nuclear antigen. The core function of LANA is to act as an “anchor” for the viral genome, attaching it to the chromatin of the host cell. LANA ensures that the episomal DNA of KSHV replicates together with the host chromosome and is evenly distributed among the daughter cells, thereby maintaining the latent infection of the virus in the cell population. LANA can regulate the transcription of viral and host cell genes, and regulate certain host cell genes to promote cell survival. LANA can be used to study the viral DNA tethering structure. |
| Sequence | Met-Ala-Pro-Pro-Gly-Met-Arg-Leu-Arg-Ser-Gly-Arg-Ser-Thr-Gly-Ala-Pro-Leu-Thr-Arg-Gly-Ser-Cys |
| Sequence Shortening | MAPPGMRLRSGRSTGAPLTRGSC |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
