Gramicidin A
Description
Gramicidin A is a peptide component of Gramicidin, a mixture of antibiotics originally isolated from B. brevis. Gramicidin A is a highly hydrophobic channel-forming ionophore that forms monovalent cation-permeable channels in artificial membranes. Gramicidin A induces the degradation of hypoxia-inducible factor 1?? (HIF-1??).
Product Details
| Product Name | Gramicidin A |
| Biological activity | Gramicidin A is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis. Gramicidin A is a highly hydrophobic channel-forming ionophore that forms channels in model membranes that are permeable to monovalent cations. Gramicidin A induces degradation of hypoxia inducible factor 1 ?? (HIF-1??). |
| Molecular Weight | 1882.29 |
| Formula | C99H140N20O17 |
| CAS Number | 11029-61-1 |
| Color | White to off-white |
| Sequence | {For}-Val-Gly-Ala-{D-Leu}-Ala-{D-Val}-Val-{D-Val}-Trp-{D-Leu}-Trp-{D-Leu}-Trp-{D-Leu}-Trp-{NHCH2CH2OH} |
| Storage | Sealed storage, away from moisture |
