Citrocin
Description
Citrocin is a potent inhibitor of bacterial RNA polymerase (RNAP). Citrocin shows significant inhibitory activity against Escherichia coli RNA polymerase, with MIC values ranging from 16 to 125 ??M. Citrocin specifically binds to RNA polymerase and inhibits its activity, thereby blocking bacterial transcription, and enters cells mainly through the inner membrane protein SbmA. Citrocin is expected to be used in research on Gram-negative bacterial infections, such as enterohemorrhagic E. coli.
Product Details
| Product Name | Citrocin |
| Biological activity | Citrocin is a potent bacterial RNA polymerase (RNAP) inhibitor. Citrocin shows significant inhibitory activity against Escherichia coli RNAP with an MIC range of 16-125 ??M. Citrocin specifically binds to and inhibits RNA polymerase to block bacterial transcription and enters cells mainly through inner membrane protein SbmA. Citrocin is promising for research of Gram-negative bacterial infections, such as enterohemorrhagic E. coli. |
| Sequence | cyclo{Gly-Gly-Val-Gly-Lys-Ile-Ile-Glu}-Tyr-Phe-Ile-Gly-Gly-Gly-Val-Gly-Arg-Tyr-Gly |
| Sequence Shortening | cyclo{GGVGKIIE}YFIGGGVGRYG |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
