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Actagardin

Description

Actagardin is a tetracyclic lantibiotic produced by several motile actinomycetes. It consists of macrocycles formed by thioether bridges. Actagardin mainly targets Gram-positive bacteria and inhibits peptidoglycan synthesis.

Product Details

Product Name Actagardin
Biological activity Actagardin is a tetracyclic lantibiotic produced by several species of Actinoplanes. It is composed of macrocyclic rings formed by thioether bridges. Actagardin preferably targets Gram-positive bacteria, inhibiting the synthesis of peptidoglycan.
Sequence {Cys}{Ser}{Gly}{Trp}{Val}{Cys}{Cys}{Leu}{Cys}{Ile}{Cys}{Gly}{Cys}{Val}{Ile}{Cys}{Ala}{Cys} (Carba sulfide bridge:Cys1-Cys6,Cys7-Cys12,Cys9-Cys17,Cys14-Cys19)
Sequence Shortening CSGWVCCLCICGCVICAC (Carba sulfide bridge:Cys1-Cys6,Cys7-Cys12,Cys9-Cys17,Cys14-Cys19)
Storage Please store the product under the recommended conditions in the Certificate of Analysis.