Tetracosactide
Description
Tetracosactide (Tetracosactrin) is an analogue of adrenocorticotrophic hormone (ACTH). Tetracosactide is the agonist for melanocortin-4 receptor (MC4R) that activates human MC4R with an EC50 of 0.65 nM. Tetracosactide can stimulate the release of corticosteroids such as cortisol from the adrenal gland. Tetracosactide is currently used for the research of ulcerative colitis and Crohn’s disease, juvenile/adult rheumatoid arthritis and osteoarthrosis.
Product Information
| Product Name | Tetracosactide |
| Molecular Weight | 2933.44 |
| Formula | C136H210N40O31S |
| CAS Number | 16960-16-0 |
| Appearance | Solid |
| Color | White to off-white |
| Sequence | Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro |
| Sequence Shortening | SYSMEHFRWGKPVGKKRRPVKVYP |
| Storage | Sealed storage, away from moisture and light, under nitrogen Powder -80??C 2 years -20??C 1 year *In solvent : -80??C, 6 months; -20??C, 1 month (sealed storage, away from moisture and light, under nitrogen) |
