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Tetracosactide acetate

Description

Tetracosactide acetate (Tetracosactrin acetate ) is the acetate salt form of Tetracosactide (HY-P0060). Tetracosactide acetate is an analogue of adrenocorticotrophic hormone (ACTH). Tetracosactide acetate is the agonist for melanocortin-4 receptor (MC4R) that activates human MC4R with an EC50 of 0.65 nM. Tetracosactide acetate can stimulate the release of corticosteroids such as cortisol from the adrenal gland. Tetracosactide acetate is currently used for the research of ulcerative colitis and Crohn’s disease, juvenile/adult rheumatoid arthritis and osteoarthrosis.

Product Information

Product Name Tetracosactide acetate
Formula C136H210N40O31S.xC2H4O2
CAS Number 60189-34-6
Appearance Solid
Color White to off-white
Sequence Shortening SYSMEHFRWGKPVGKKRRPVKVYP
Sequence Shortening SYSMEHFRWGKPVGKKRRPVKVYP
Storage Sealed storage, away from moisture and light, under nitrogen Powder -80??C 2 years -20??C 1 year *In solvent : -80??C, 6 months; -20??C, 1 month (sealed storage, away from moisture and light, under nitrogen)