SKF 106760
Description
SKF 106760 is a potent platelet fibrin receptor (glycoprotein IIb/IIIa) antagonist with significant antiplatelet and antithrombotic activities. SKF 106760 inhibits platelet aggregation in dogs in vitro and prevents thrombus formation in stenotic carotid arteries. SKF 106760 has also shown elimination effects against aspirin-resistant thrombi that develop in the setting of high-grade stenosis.
Product Information
| Product Name | SKF 106760 |
| Molecular Weight | 633.74 |
| Formula | C23H39N9O8S2 |
| CAS Number | 126053-71-2 |
| Sequence | Ac-Cys-{(NMe)Arg}-Gly-Asp-{Pen}-NH2 (Disulfidebridge:Cys1-Pen5) |
| Sequence Shortening | Ac-C-{(NMe)Arg}-GD-{Pen}-NH2 (Disulfidebridge:Cys1-Pen5) |
