Salivaricin B
Description
Salivaricin B is a broad-spectrum bacteriocin that can be produced by Lactobacillus M7. Salivaricin B reduces cell wall thickness, leading to abnormal septum formation, and exerts rapid bactericidal activity against susceptible Gram-positive bacteria without disrupting cytoplasmic membrane integrity or dissipating membrane potential. Salivaricin B inhibits the growth of Gram-positive pathogens of the oral cavity, upper respiratory tract, and food-related sources, spoilage bacteria, lactobacilli, and Streptococcus salivarius strains that do not produce SboB; its activity is strain-dependent and it has no effect on Gram-negative bacteria. Salivaricin B can be used in research related to bacterial infections.
Product Details
| Product Name | Salivaricin B |
| Biological activity | Salivaricin B is a broad-spectrum bacteriocin produced by Lactobacillus M7. Salivaricin B reduces cell wall thickness, induces abnormal septum formation, and exerts rapid bactericidal activity against susceptible Gram-positive bacteria without disrupting cytoplasmic membrane integrity or dissipating membrane potential. Salivaricin B inhibits the growth of oral, upper respiratory tract and food-related Gram-positive pathogens, spoilage bacteria, lactobacilli, and SboB-non-producing Streptococcus salivarius strains. Its activity is strain-dependent, and it has no effect on Gram-negative bacteria. Salivaricin B can be used in studies related to bacterial infections. |
| CAS Number | 335080-41-6 |
| Appearance | Solid |
| Color | White to off-white |
| Sequence | Gly-Gly-Gly-Val-Ile-Gln-Thr-Ile-Ser-His-Glu-Cys-Arg-Met-Asn-Ser-Trp-Gln-Phe-Leu-Phe-Thr-Cys-Cys-Ser |
| Sequence Shortening | GGGVIQTISHECRMNSWQFLFTCCS |
| Storage | Sealed storage, away from moisture |
