Pasireotide acetate
Description
Pasireotide (SOM230) acetate, a long-acting cyclohexapeptide somatostatin analogue, can improve agonist activity at somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9, respectively). Pasireotide acetate can suppress GH, IGF-I and ACTH secretion, indicating potential efficacy in acromegaly and Cushing's disease. Pasireotide acetate also exhibits antisecretory, antiproliferative, and proapoptotic activity.
Product Information
| Product Name | Pasireotide acetate |
| Molecular Weight | 1107.26 |
| Formula | C60H70N10O11 |
| CAS Number | 396091-76-2 |
| Appearance | Solid |
| Color | White to off-white |
| Sequence | Cyclo |
| Sequence Shortening | Cyclo |
| Storage | Sealed storage, away from moisture and light, under nitrogen Powder -80??C 2 years -20??C 1 year *In solvent : -80??C, 6 months; -20??C, 1 month (sealed storage, away from moisture and light, under nitrogen) |
