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Linaclotide

Description

Linaclotide is a potent and selective guanylate cyclase C agonist; developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation.

Product Information

Product Name Linaclotide
Molecular Weight 1526.74
Formula C59H79N15O21S6
CAS Number 851199-59-2
Appearance Solid
Color White to off-white
Sequence Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr (disulfide bridge:Cys1-Cys6,Cys2-Cys10,Cys5-Cys13)
Sequence Shortening CCEYCCNPACTGCY (disulfide bridge:Cys1-Cys6,Cys2-Cys10,Cys5-Cys13)
Storage Sealed storage, away from moisture Powder -80??C 2 years -20??C 1 year *In solvent : -80??C, 6 months; -20??C, 1 month (sealed storage, away from moisture)