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Linaclotide acetate

Description

Linaclotide acetate is a potent and selective guanylate cyclase C agonist; developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation.

Product Information

Product Name Linaclotide acetate
Molecular Weight 1586.79
Formula C61H83N15O23S6
CAS Number 851199-60-5
Appearance Solid
Color White to off-white
Sequence Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr (disulfide bridge: Cys1-Cys6; Cys2-Cys10; Cys5-Cys13)
Sequence Shortening CCEYCCNPACTGCY (disulfide bridge: Cys1-Cys6; Cys2-Cys10; Cys5-Cys13)
Storage Sealed storage, away from moisture Powder -80??C 2 years -20??C 1 year *In solvent : -80??C, 6 months; -20??C, 1 month (sealed storage, away from moisture)