(K(C10)GGGRrRPC)2
Description
(K(C10)GGGRrRPC)2 (Compound (C-C10)C-C) is a dimeric lipopeptide and antibacterial agent. (K(C10)GGGRrRPC)2 enhances the accumulation of reactive oxygen species (ROS) and inhibits the activity of bacterial respiratory chain dehydrogenase. (K(C10)GGGRrRPC)2 significantly inhibits bacterial biofilm formation. (K(C10)GGGRrRPC)2 has antibacterial activity against Acinetobacter baumannii AB1901, Acinetobacter baumannii AB1902, Pseudomonas aeruginosa 25349, and Staphylococcus aureus 11011, with MIC values of 4 ??M, 8 ??M, 4 ??M, and 8 ??M, respectively. (K(C10)GGGRrRPC)2 also shows antibacterial effects against E. coli ATCC 25922.
Product Details
| Product Name | (K(C10)GGGRrRPC)2 |
| Biological activity | (K(C10)GGGRrRPC)2 (Compound (C-C10)C-C) is a dimeric lipopeptide and antibacterial agent. (K(C10)GGGRrRPC)2 enhances the accumulation of ROS, inhibits the bacterial respiratory chain dehydrogenase activity. (K(C10)GGGRrRPC)2 exhibits significant inhibition of bacterial biofilm formation. (K(C10)GGGRrRPC)2 exhibits antimicrobial activity against Acinetobacter baumannii AB1901, A. baumannii AB1902, Pseudomonas aeruginosa 25349, Staphylococcus aureus 11011, with MICs of 4 ??M, 8 ??M, 4 ??M, and 8 ??M, respectively. (K(C10)GGGRrRPC)2 shows antimicrobial efficacy against E. coli ATCC 25922. |
| Sequence Shortening | {Lys(decanal)}-GGGR-{d-Arg}-RRPCCPRR-{d-Arg}-RGGG-{Lys(decanal)} (Disulfide bridge: Cys9-Cys10) |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
