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Imapextide

Description

Imapextide (MBX 1416) is a selective, reversible glucagon-like peptide-1 receptor (GLP-1R) antagonist. Imapextide selectively and reversibly modulates GLP-1R, reverses the effects of GLP-1 agonists, and abolishes agonist-induced anorectic and weight-lowering activities. Imapextide can be used in the research of post-bariatric hypoglycemia.

Product Information

Product Name Imapextide
Molecular Weight 3599.05
Formula C166H257N39O50
CAS Number 3004569-93-8
Appearance Solid
Color White to off-white
Sequence {C18 diacid-Asp}-Val-Ser-Ser-Tyr-Leu-Glu-Glu-Gln-Ala-Val-Arg-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser
Sequence Shortening {C18 diacid-Asp}-VSSYLEEQAVREFIAWLVRGGPSSGAPPPS
Storage Sealed storage, away from moisture Powder -80??C 2 years -20??C 1 year *In solvent : -80??C, 6 months; -20??C, 1 month (sealed storage, away from moisture)