Griselimycin
Description
Griselimycin is a cyclic depsipeptide that can be produced by Streptomyces. Griselimycin specifically binds to the bacterial DNA polymerase sliding clamp and does not interact with human PCNA. Griselimycin has potent antibacterial activity against Mycobacterium tuberculosis (including drug-resistant strains) and a variety of Gram-negative bacteria.
Product Details
| Product Name | Griselimycin |
| Biological activity | Griselimycin is a cyclic lipopeptide produced by Streptomyces. Griselimycin specifically binds to the sliding clamp of bacterial DNA polymerase and does not interact with human PCNA. Griselimycin exhibits potent antibacterial activity against Mycobacterium tuberculosis (including drug-resistant strains) and a variety of Gram-negative bacteria. |
| CAS Number | 26034-16-2 |
| Appearance | Solid |
| Color | White to off-white |
| Storage | Sealed storage, away from moisture |
