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Ganirelix

Description

Ganirelix is a competitive and selective gonadotropin releasing hormone (GnRH) antagonist. Ganirelix prevents endogenous GnRH from inducing luteinising hormone (LH) and follicle stimulating hormone release. Ganirelix counteracts Prostaglandin E2 (HY-101952)-induced detrusor overactivity, enhances Carbachol (HY-B1208)-induced detrusor contractions. Ganirelix can be used for the research of female infertility and detrusor overactivity.

Product Information

Product Name Ganirelix
Molecular Weight 1570.32
Formula C80H113ClN18O13
CAS Number 124904-93-4
Appearance Solid
Color White to off-white
Sequence Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-{Har(Et,Et)}-Leu-{Har(Et,Et)}-Pro-D-Ala-NH2
Sequence Shortening Ac-{D-2Nal}-{D-Phe(4-Cl)}-{D-3Pal}-SY-{D-Har(Et,Et)}-L-{Har(Et,Et)}-P-{D-Ala}-NH2
Storage Sealed storage, away from moisture Powder -80??C 2 years -20??C 1 year *In solvent : -80??C, 6 months; -20??C, 1 month (sealed storage, away from moisture)