Cotadutide
Description
Cotadutide (MEDI0382) is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC50 values of 6.9 pM and 10.2 pM, respectively. Cotadutide exhibits ability to facilitate both weight loss and glycaemic control, and alleviate fibrosis. Cotadutide can be used in the research of obesity and type 2 diabetes (T2D).
Product Information
| Product Name | Cotadutide |
| Molecular Weight | 3728.09 |
| Formula | C167H252N42O55 |
| CAS Number | 1686108-82-6 |
| Appearance | Solid |
| Color | White to off-white |
| Sequence | His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-{Lys(γGlu-C16 acid)}-Ser-Glu-Tyr-Leu-Asp-Ser-Glu-Arg-Ala-Arg-Asp-Phe-Val-Ala-Trp-Leu-Glu-Ala-Gly-Gly |
| Sequence Shortening | HSQGTFTSD-{Lys(γGlu-C16 acid)}-SEYLDSERARDFVAWLEAGG |
| Storage | Sealed storage, away from moisture Powder -80??C 2 years -20??C 1 year *In solvent : -80??C, 6 months; -20??C, 1 month (sealed storage, away from moisture) |
