Cenderitide
Description
Cenderitide is a potent agonist of particulate guanylyl cyclase receptor (pGC). Cenderitide is a natriuretic peptide (NP) composed of C-type natriuretic peptide (CNP) fused to the C-terminus of Dendroaspis natriuretic peptide (DNP). Cenderitide activates both pGC-A and pGC-B, activates the second messenger cGMP, suppresses aldosterone, and preserves GFR without reducing blood pressure. Cenderitide can be used for heart failure research.
Product Information
| Product Name | Cenderitide |
| Molecular Weight | 3745.27 |
| Formula | C158H263N49O50S3 |
| CAS Number | 507289-11-4 |
| Appearance | Solid |
| Color | White to off-white |
| Sequence | Shortening GLSKGCFGLKLDRIGSMSGLGCPSLRDPRPNAPSTSA (Disulfide bridge:Cys6-Cys22) |
| Sequence Shortening | GLSKGCFGLKLDRIGSMSGLGCPSLRDPRPNAPSTSA (Disulfide bridge:Cys6-Cys22) |
| Storage | Sealed storage, away from moisture Powder -80??C 2 years -20??C 1 year *In solvent : -80??C, 6 months; -20??C, 1 month (sealed storage, away from moisture) |
