CBP-501 acetate
Description
CBP-501 acetate, a cell-permeable calmodulin-binding peptide and a G2-abrogating drug candidate, inhibits the activity of multiple Ser216-specific kinases, such as MAPKAP-K2, C-Tak1, CHK1 and CHK2, with IC50 values of 0.9 ??M, 1.4 ??M 3.4 ??M and 6.5 ??M, respectively. CBP-501 acetate is used for various types of cancer.
Product Information
| Product Name | CBP-501 acetate |
| Molecular Weight | 1929.06 (free base) |
| Formula | C86H122F5N29O17.xC2H4O2 |
| Appearance | Solid |
| Color | White to off-white |
| Sequence | d({4-Bz-Phe}-Ser-Trp-Ser-{pentafluoro-Phe}-{Cha}-Arg-Arg-Arg-Gln-Arg-Arg) |
| Sequence Shortening | d({4-Bz-Phe}-SWS-{pentafluoro-Phe}-{Cha}-RRRQRR) |
| Storage | Sealed storage, away from moisture Powder -80??C 2 years -20??C 1 year *In solvent : -80??C, 6 months; -20??C, 1 month (sealed storage, away from moisture) |
