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Canvuparatide

Description

Canvuparatide (MBX 2109) is a PTH analog prodrug that releases the biologically active peptide through temperature- and pH-controlled intramolecular cyclization. The peptide released by Canvuparatide binds to and activates the PTH1 receptor, stimulating dose-dependent cAMP accumulation. Canvuparatide can be used in research on hypoparathyroidism.

Product Information

Product Name Canvuparatide
Molecular Weight 5873.83
Formula C263H441N65O81S2
CAS Number 2925554-87-4
Appearance Solid
Color White to off-white
Sequence DLys(γ-Glu-PEG2-PEG2-17-carboxyheptadecanoyl)-Sar-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Lys(γ-Glu-PEG2-PEG2-17-carboxyheptadecanoyl)
Storage Sealed storage, away from moisture Powder -80??C 2 years -20??C 1 year *In solvent : -80??C, 6 months; -20??C, 1 month (sealed storage, away from moisture)