ABT-510
Description
ABT-510 is an anti-angiogenic TSP peptide (Thrombospondin-1 analogue) that induces apoptosis and inhibits ovarian tumour growth in an orthotopic, syngeneic model of epithelial ovarian cancer. ABT-510 also reduces angiogenesis and inflammatory responses in a murine model of inflammatory bowel disease. ABT-510 can be used in studies of cancer (particularly epithelial ovarian cancer) and inflammatory bowel disease (IBD).
Product Information
| Product Name | ABT-510 |
| Molecular Weight | 994.23 |
| Formula | C46H83N13O11 |
| CAS Number | 251579-55-2 |
| Appearance | Solid |
| Color | White to off-white |
| Sequence | Ac-{Sar}-Gly-Val-{D-Allo-Ile}-Thr-{Nva}-Ile-Arg-{Pro-NHEt} |
| Sequence Shortening | Ac-{Sar}-GV-{D-Allo-Ile-T-{Nva}-IR-{Pro-NHEt} |
| Storage | Sealed storage, away from moisture Powder -80??C 2 years -20??C 1 year *In solvent : -80??C, 6 months; -20??C, 1 month (sealed storage, away from moisture) |
