Myelin Basic Protein

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Myelin basic protein (MBP) is a protein in nerve myelination process, it is the major constituent of the oligodendrocyte myelin and Sehwann cells in the central nervous system. MBP maintains the correct structure of myelin, and interacts with the lipids in myelin membrane.

The MBPs in the central nervous system are very diverse, including: several splice variants, post-translational modifications (phosphorylation, methylation, deamidation, and citrullination).

Notice: All peptides are only for research purposes, Not for clinical use.

MBP Peptides

1.Myelin Basic Protein (87-99) (human, bovine, rat),MBP (87-99), guinea pig, human
  • Name: Myelin Basic Protein (87-99) (human, bovine, rat),MBP (87-99), guinea pig, human
  • Sequence: VHFFKNIVTPRTP
  • CAS Number: [118506-26-6]
  • Formula: C74H114N20O17
  • Characteristics: None
  • Reference: R.E.Jones et al., J. Neuroimmunol., 37, 203 (1992)
2.Acetyl-Myelin Basic Protein (135-145)) (human)
  • Name: Acetyl-Myelin Basic Protein (135-145) (human)
  • Sequence: Ac-ASQKRPSQRHG
  • CAS Number: [106128-98-7]
  • Formula: C52H88N22O17
  • Characteristics: None
  • Reference: B.Metzler and D.C.Wraith, Int. Immunol., 5, 1159 (1993) J.E. Fenyk-Melody, A.E. Garrison, S.R. Brunnert, J.R. Weidner, F. Shen, B.A. Shelton, and J.S. Mudgett,J. Immunol., 160, 2940 (1998)
3.MBP (68-82),Myelin Basic Protein (68-84), guinea pig
  • Name: MBP (68-82),Myelin Basic Protein (68-84), guinea pig
  • Sequence: YGSLPQKSQRSQDEN
  • CAS Number: [98474-59-0]
  • Formula: C71H113N23O28
  • Characteristics: None
  • Reference: None
4.PLP (139-151)Myelin Proteolipid Protein (139-151))(depMyelin Proteolipid Protein (139-151) (depalmitoylated) (human, bovine, dog
  • Name: PLP (139-151)|Myelin Proteolipid Protein (139-151))|(depMyelin Proteolipid Protein (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat)
  • Sequence: HCLGKWLGHPDKF
  • CAS Number: [131334-43-5]
  • Formula: C72H104N20O16S1
  • Characteristics: None
  • Reference: S.Youssef et al., Nature, 420, 78 (2002)  Gonzalez-Rey, E. et al. Am. J. Pathol. 168, 1179 (2006)
5.Myelin Oligodendrocyte Glycoprotein (MOG 35-55), rat, mouse
  • Name: Myelin Oligodendrocyte Glycoprotein (MOG 35-55), rat, mouse
  • Sequence: MEVGWYRSPFSRVVHLYRNGK
  • CAS Number: [163913-87-9]
  • Formula: C118H177N35O29S1
  • Characteristics: None
  • Reference: Le Moan, Natacha, et al. Eneuro 2.2 (2015): ENEURO-0050.  Dupree, Jeffrey L., et al. Journal of Neurochemistry 134.2 (2015): 302-314.  Orozco, Juan L. Hancke, and Rafael Burgos. U.S. Patent No. 9,060,994. 23 Jun. 2015
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