Luteinizing Hormone-Releasing Hormone

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Luteinizing hormone-releasing hormone(LHRH, LH-RH) is a hormone secreted by the hypothalamus. It stimulates the brain to secrete the luteinizing hormone (LH) and follicle-stimulating hormone (FSH). It is also called gonadotropin-releasing hormone (GnRH).

LHRH is a hypothalamic hormone, it controls the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in the pituitary gland. It has interaction with specific G-protein-coupled receptors, then stimulates the secretion of gonadotropins. LH-RH is not only a neurohormone, but also a neurotransmitter or neuromodulator.

Notice: All peptides are only for research purposes, Not for clinical use.

LHRH Peptides

1.LH-RH, human, Gonadoreline
  • Name: LH-RH, human, Gonadoreline
  • Sequence: (Glp)-HWSYGLRPG-NH2
  • CAS Number: [71447-49-9]
  • Formula: C55H75N17O13
  • Characteristics: None
  • Reference: E. Rivier et al., Life Sci. 23, 869 (1978)  D. Tilemans et al., Endocrinology, 130, 887 (1992)
2.LH-RH, Free Acid
  • Name: LH-RH, Free Acid
  • Sequence: (Glp)-HWSYGLRPG
  • CAS Number: None
  • Formula: C55H74N16O14
  • Characteristics: None
  • Reference: J. Rivier et al., Life Sci., 23, 869 (1978)
3.[DTrp6]-LH-RH, amide
  • Name: [DTrp6]-LH-RH, amide
  • Sequence: (Glp)-HWSYwLRPG-NH2 (Remark: w is D-Trp)
  • CAS Number: None
  • Formula: C64H82N18O13
  • Characteristics: None
  • Reference: None
4.[Des-Gly10, DLeu6, Pro9]-LH-RH, Ethyl Amid
  • Name: [Des-Gly10, DLeu6, Pro9]-LH-RH, Ethyl Amid
  • Sequence: (Glp)-HWSYlLRP-NHET (Remark: l is D-Leu)
  • CAS Number: None
  • Formula: C59H84N16O12
  • Characteristics: None
  • Reference: None
5.LH-RH, salmon
  • Name: LH-RH, salmon
  • Sequence: (Glp)-HWSYGWLPG-NH2
  • CAS Number: None
  • Formula: C60H73N15O13
  • Characteristics: None
  • Reference: None
6.LH-RH, lamprey
  • Name: LH-RH, lamprey
  • Sequence: (Glp)-HYSLEWKPG-NH2
  • CAS Number: None
  • Formula: C58H79N15O15
  • Characteristics: None
  • Reference: N.M. Sherwood et al., JBC, 261, 4812 (1986)
7.LHRH II
  • Name: LHRH II
  • Sequence: (Pyr)-HWSHGWYPG-NH2
  • CAS Number: [91097-16-4]
  • Formula: C60H69N17O13
  • Characteristics: None
  • Reference: J.F.Powell et al., Regul. Peptides, 57, 43 (1995)  J.F.Powell et al., Regul. Peptides, 68, 189 (1997)
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