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Orexin B, human acetate

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Description

Product Name Neurokinin B TFA
Biological activity Neurokinin B TFA is a tachykinin family peptide that preferentially binds to and activates NK3R over other tachykinin receptors. Neurokinin B TFA preferentially binds to the substance P receptor (SP-N receptor) and mediates acetylcholine release from cholinergic neurons. Neurokinin B TFA regulates the pulsatile release of Kisspeptin and GnRH, stimulates or inhibits the secretion of luteinizing hormone (HY-P2293), regulates reproductive function via metabolic signals, and drives the onset of puberty. Neurokinin B TFA exerts vasoactive effects and induces contraction of isolated guinea pig ileum. Neurokinin B TFA can be used in studies related to hypogonadotropic hypogonadism.
Molecular Weight 1438.47
Formula Formula C55H79N13O14S2.2C2HF3O2
CAS Number 101536-55-4
Appearance Solid
Color White to off-white
Sequence Sequence Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2
Sequence Shortening Sequence Shortening DMHDFFVGLM-NH2