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Neurogranin (48-76), human

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Description

Product Name Isotocin
Biological activity Isotocin is the homologue of mammalian oxytocin in teleost fish, belonging to the category of neurotransmitters/neuromodulators and peripheral hormones. Isotocin exerts biological effects by binding to its homologous isotocin receptor (with EC50 = 1.58e-10 mol/L in gilthead seabream) and specific G-protein-coupled receptor subtypes. Isotocin promotes paternal behavior in cichlids, regulates the expression of Foxi3a and P63, thereby controlling the differentiation of ionocyte progenitor cells and the proliferation of epidermal stem cells, and modulates whole-body ion content in zebrafish embryos. Isotocin regulates social and reproductive behaviors, synchronizes the reproductive cycles of teleost fish, and its neuronal phenotypes can be used to classify the types of reproductive systems in cichlids.
Molecular Weight 966.14
Formula Formula C41H63N11O12S2
CAS Number 550-21-0
Sequence Sequence Cys-Tyr-Ile-Ser-Asn-Cys-Pro-Ile-Gly-NH2 (Disulfide bridge: Cys1-Cys6)
Sequence Shortening Sequence Shortening CYISNCPIG-NH2 (Disulfide bridge: Cys1-Cys6)
Storage Please store the product under the recommended conditions in the Certificate of Analysis.