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Magainin 2

Description

Magainin 2 (Magainin II) is an antimicrobial peptide (AMP) isolated from the skin of the African clawed frog. Magainin 2 shows antibiotic activity against many Gram-negative and Gram-positive bacteria. Magainin 2 is also active against protozoa. Magainin 2 exerts cytotoxic effects by preferentially interacting with anionic phospholipids that are abundant in bacterial membranes.

Product Details

Product Name Magainin 2
Biological activity Magainin 2 (Magainin II) is an antimicrobial peptide (AMP) isolated from the skin of the African clawed frog Xenopus laevis. Magainin 2 displays antibiotic activity against numerous gram-negative and gram-positive bacteria. Magainin 2 also is active against protozoa. Magainin 2 exerts its cytotoxicity effects by preferential interactions with anionic phospholipids abundant in bacterial membranes.
CAS Number 108433-95-0
Appearance Solid
Color White to off-white
Sequence Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Asn-Ser
Sequence Shortening GIGKFLHSAKKFGKAFVGEIMNS