PACAP (1-38), human, ovine, rat

PACAP (1-38), a novel neuropeptide isolated from the bovine hypothalamus is more active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50=7 nM). PACAP 1-38 (10-9 M) increased substance P (SP), gastrin releasing peptide (GRP), and VIP release. PACAP 1-38 (10-8 M) inhibited gastrin secretion and stimulated somatostatin secretion and motility dose-dependently.

Category:

Description

Purity
> 95%
Solubility
Soluble in Ultrapure water under 1mg/ml
Form
Lyophilized
Storage
Store the peptide at -20°C.
Note
PACAP stimulates adenylate cyclase in rat anterior pituitary cells.

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